首页> 外文会议>Electrochemical Society(ECS) Meeting;Symposium on Surface Treatments for Biomedical Applications; 20071007-12;20071007-12; Washington,DC(US);Washington,DC(US) >Treatment of Various Surfaces with Silver and its Compounds for Topical Wound Dressings, Catheter and Other Biomedical Applications
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Treatment of Various Surfaces with Silver and its Compounds for Topical Wound Dressings, Catheter and Other Biomedical Applications

机译:银及其化合物对局部伤口敷料,导管和其他生物医学应用的各种表面的处理

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摘要

The applications of surfaces treated with silver and its compounds include devices used as topical wound dressings, urinary catheters, endotracheal tubes, cardiac valves etc. Treatment of surfaces e.g. textile, polymers or metals with silver or its compounds is carried out to achieve the antimicrobial action of silver ions. Several approaches of surface treatment of medical devices for the antimicrobial purposes, such as electrodeposition, electroless deposition, physical vapor deposition, γ - radiation, etc. have been used in practice. It is clear that only silver ions are responsible for the antimicrobial activity. As confirmed experimentally, only samples containing silver compounds can deliberate silver ions in the tested media and exhibit antimicrobial activity both in vitro and in vivo. There is no evidence that elemental silver, even its so-called "nano-crystalline" state, exhibits an antimicrobial activity. Consequently, the devices coated with "nano-crystalline" silver should carefully be taken into consideration before the application.
机译:用银及其化合物处理过的表面的应用包括用作局部伤口敷料,导尿管,气管插管,心脏瓣膜等的装置。纺织品,聚合物或金属与银或其化合物的结合可实现银离子的抗菌作用。在实践中已经使用了几种用于抗菌目的的医疗器械表面处理方法,例如电沉积,化学沉积,物理气相沉积,γ-辐射等。显然,只有银离子负责抗菌活性。经实验证实,只有含银化合物的样品才能在被测介质中考虑银离子,并在体外和体内均显示出抗菌活性。没有证据表明元素银,甚至其所谓的“纳米晶”状态也表现出抗菌活性。因此,在使用前应仔细考虑涂有“纳米晶体”银的器件。

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