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首页> 外文会议>Emerging and endemic pathogens : Advances in surveillance, detection and identification >Environmental Influences on the Relative Stability of Baculoviruses and Vaccinia Virus: A Review
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Environmental Influences on the Relative Stability of Baculoviruses and Vaccinia Virus: A Review

机译：环境对杆状病毒和牛痘病毒相对稳定性的影响：综述

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摘要

The environmental fate of viruses is a topic of recent interest because the transport and fate of viruses in the environment may impact human and animal health. In studying the transport of pathogenic viruses in the environment some workers have used non-pathogenic surrogate or "simulant" viruses as tracer organisms for safety reasons. In an effort to identify simulants for orthopoxviruses, the use of baculoviruses has been proposed. Like poxviruses, they are also large, ds-DNA viruses. Unlike poxviruses, however, they are generally regarded as harmless to plants and animals outside their narrow insect host range and have been broadly disseminated for decades in organic agriculture as natural insecticides. The use of baculoviruses as simulants for the development of decontaminants requires an understanding of the relative resistance of both poxviruses and baculoviruses to environmental stressors, so that their relative, inherent rates of environmental degradation can be accounted for in determining whether a candidate decontamination regime is effective. To this end, we review here what is known about the susceptibility of baculoviruses and poxviruses to environmental stressors (temperature, UV light, moisture and pH) and the influence of their physical environments (soil, phyllosphere, or aquatic surroundings).
机译：病毒的环境命运是最近引起关注的话题，因为病毒在环境中的运输和命运可能会影响人类和动物的健康。在研究环境中病原性病毒的运输时，出于安全原因，一些工人已使用非病原性替代病毒或“模拟”病毒作为示踪生物。为了鉴定正痘病毒的模拟物，已经提出了杆状病毒的用途。像痘病毒一样，它们也是大型的ds-DNA病毒。然而，与痘病毒不同，它们通常被认为对昆虫宿主范围较窄的动植物无害，并已作为天然杀虫剂在有机农业中广泛传播了数十年。使用杆状病毒作为模拟物开发去污剂需要了解痘病毒和杆状病毒对环境胁迫的相对抗性，以便可以在确定候选去污制度是否有效时考虑其相对的固有环境降解速率。 。为此，我们在这里回顾一下杆状病毒和痘病毒对环境胁迫（温度，紫外线，水分和pH）的敏感性以及其物理环境（土壤，叶际层或水生环境）的影响。

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