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A novel parameter for predicting arterial fusion and ablation in finite element models

机译：预测有限元模型中动脉融合和消融的新参数

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摘要

Tissue fusion devices apply heat and pressure to ligate or ablate blood vessels during surgery. Although this process is widely used, a predictive finite element (FE) model incorporating both structural mechanics and heat transfer has not been developed, limiting improvements to empirical evidence. This work presents the development of a novel damage parameter, which incorporates stress, water content and temperature, and demonstrates its application in a FE model. A FE model, using the Holzapfel-Gasser-Ogden strain energy function to represent the structural mechanics and equations developed by Cezo to model water content and heat transfer, was created to simulate the fusion or ablation of a porcine splenic artery. Using state variables, the stresses, temperature and water content are recorded and combined to create a single parameter at each integration point. The parameter is then compared to a critical value (determined through experiments). If the critical value is reached, the element loses all strength. If the value is not reached, no change occurs. Little experimental data exists for validation, but the resulting stresses, temperatures and water content fall within ranges predicted by prior work. Due to the lack of published data, additional experimental studies are being conducted to rigorously validate and accurately determine the critical value. Ultimately, a novel method for demonstrating tissue damage and fusion in a FE model is presented, providing the first step towards in-depth FE models simulating fusion and ablation of arteries.
机译：组织融合装置在手术过程中施加热量和压力以结扎或消融血管。尽管此过程得到了广泛使用，但尚未开发出将结构力学和热传递都结合在一起的预测性有限元（FE）模型，从而限制了对经验证据的改进。这项工作提出了一种新的损伤参数的开发方法，该参数综合了应力，水含量和温度，并证明了其在有限元模型中的应用。建立了一个使用Holzapfel-Gasser-Ogden应变能函数表示由Cezo开发的用于模拟水含量和热传递的结构力学和方程的有限元模型，以模拟猪脾动脉的融合或消融。使用状态变量，记录应力，温度和水含量，并将其组合在一起，以在每个积分点创建一个参数。然后将参数与临界值（通过实验确定）进行比较。如果达到临界值，则元素将失去所有强度。如果未达到该值，则不会发生任何变化。几乎没有用于验证的实验数据，但是由此产生的应力，温度和水含量都在先前工作预测的范围内。由于缺乏公开的数据，正在进行其他实验研究，以严格验证和准确确定临界值。最终，提出了一种在FE模型中证明组织损伤和融合的新方法，为深入模拟动脉融合和消融的FE模型提供了第一步。

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