3D/4D Multiscale Imaging in Acute Lymphoblastic Leukemia cells- visualizing dynamics of cell death.

机译：急性淋巴细胞白血病细胞中的3D / 4D多尺度成像-可视化细胞死亡动态。

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Quantitative phase detection is a new methodology that provides quantitative information on cellular morphology to monitor the cell status, drug response and toxicity. In this paper the morphological changes in acute leukemia cells treated with chitosan were detected using d'Bioimager a robust imaging system. Quantitative phase image of the cells was obtained with numerical analysis. Results show that the average area and optical volume of the chitosan treated cells is significantly reduced when compared with the control cells, which reveals the effect of chitosan on the cancer cells. From the results it can be attributed that d'Bioimager can be used as a non-invasive imaging alternative to measure the morphological changes of the living cells in real time.

机译：定量相检测是一种新方法，可提供有关细胞形态的定量信息，以监测细胞状态，药物反应和毒性。本文使用耐用的成像系统d'Bioimager检测了壳聚糖处理的急性白血病细胞的形态学变化。通过数值分析获得细胞的定量相图像。结果表明，与对照细胞相比，经壳聚糖处理的细胞的平均面积和光学体积显着降低，这表明壳聚糖对癌细胞的作用。根据结果，可以认为d'Bioimager可以用作非侵入性成像替代品，以实时测量活细胞的形态变化。

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来源
《Fifth International Conference on Optical and Photonics Engineering》|2017年|1044936.1-1044936.6|共6页
会议地点 Singapore(SG)
作者
Sreelatha Sarangapani; Rosmin Elsa Mohan; Ajeetkumar Patil; Mathew J Lang; Anand Asundi;
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作者单位

BioSym, Singapore MIT Alliance for Research Technology;

School of Mechanical and Aerospace Engineering, Nanyang Technological University, Singapore;

BioSym, Singapore MIT Alliance for Research Technology;

BioSym, Singapore MIT Alliance for Research Technology;

School of Mechanical and Aerospace Engineering, Nanyang Technological University, Singapore;

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原文格式 PDF
正文语种 eng
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Chitosan; cancer cells; Phase imaging;

机译：壳聚糖癌细胞；相位成像;
入库时间 2022-08-26 14:02:08

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3D/4D Multiscale Imaging in Acute Lymphoblastic Leukemia cells- visualizing dynamics of cell death.

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