3D/4D Multiscale Imaging in Acute Lymphoblastic Leukemia cells- visualizing dynamics of cell death.

机译：3D / 4D多尺度成像在急性淋巴细胞白血病细胞 - 可视化细胞死亡动态。

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Quantitative phase detection is a new methodology that provides quantitative information on cellular morphology to monitor the cell status, drug response and toxicity. In this paper the morphological changes in acute leukemia cells treated with chitosan were detected using d'Bioimager a robust imaging system. Quantitative phase image of the cells was obtained with numerical analysis. Results show that the average area and optical volume of the chitosan treated cells is significantly reduced when compared with the control cells, which reveals the effect of chitosan on the cancer cells. From the results it can be attributed that d'Bioimager can be used as a non-invasive imaging alternative to measure the morphological changes of the living cells in real time.

机译：定量相位检测是一种新的方法，可提供有关细胞形态的定量信息，以监测细胞状态，药物反应和毒性。本文使用D'BioImager稳健的成像系统检测用壳聚糖处理的急性白血病细胞的形态变化。用数值分析获得细胞的定量相位图像。结果表明，与对照细胞相比，壳聚糖处理细胞的平均面积和光学体积显着降低，这揭示了壳聚糖对癌细胞的影响。从结果，它可以归因于D'BioImager可以用作非侵入性成像替代方案，以实时测量活细胞的形态变化。

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《International Conference on Optical and Photonics Engineering》|2017年|ix v. p.|共6页
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Sreelatha Sarangapani; Rosmin Elsa Mohan; Ajeetkumar Patil; Mathew J Lang; Anand Asundi;
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中图分类物理学;
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Chitosan; cancer cells; Phase imaging;

机译：壳聚糖;癌细胞;相显;

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3D/4D Multiscale Imaging in Acute Lymphoblastic Leukemia cells- visualizing dynamics of cell death.

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