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Photochemical surface modification of polymers for biomedical applications

机译:用于生物医学的聚合物的光化学表面改性

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We describe here the modification of various polymers (polytetrafluoroethylene, polyethyleneterephthalate, and polyvinyl alcohol) by UV-irradiation with wavelengths below 200 nm in an inert or reactive atmosphere. The light sources employed are F_2- or excimer lasers and excimer lamps. The reactive gases include ammonia (NH_3), acetylene (C_2H_2), and oxygen (O_2). Photo-dissociated fragments of these gases can react with the polymers or be deposited thereon, resulting in new chemical groups at the surface. Special emphasis is put to improved adhesion of biological cells at these modified surfaces. Potentials applications include cell coated medical implants and prostheses as well as cell micro-arrays for high throughput screening.
机译:我们在这里描述了在惰性或反应性气氛中,通过波长小于200 nm的紫外线辐射,对各种聚合物(聚四氟乙烯,聚对苯二甲酸乙二醇酯和聚乙烯醇)进行的改性。使用的光源是F_2或准分子激光器和准分子灯。反应性气体包括氨气(NH_3),乙炔(C_2H_2)和氧气(O_2)。这些气体的光解离片段可以与聚合物反应或沉积在聚合物上,从而在表面产生新的化学基团。特别强调的是改善这些修饰表面上生物细胞的附着力。潜在的应用包括细胞包被的医疗植入物和假体,以及用于高通量筛选的细胞微阵列。

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