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首页> 外文期刊>Polymer Preprints >Surface Modification or Polymers for Biomedical Applications: Chemical, Biological and Surface Analytical Challenges
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Surface Modification or Polymers for Biomedical Applications: Chemical, Biological and Surface Analytical Challenges

机译：生物医学应用的表面改性或聚合物：化学，生物学和表面分析的挑战

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Proper design, synthesis, and fabrication of biomaterials will ensure that they Surface Analysis have the appropriate mechanical properties, durability, and functionality. A few examples are a knee prosthesis that should withstand high stresses, a blood oxygenator membrane that should have the requisite permeability characteristics, and the leaflets in a heart valve that should flex for millions of cycles without failure. The bulk structure of the materials govern these properties. Biological responses to biomaterials, on the other hand, is dominated by their surface chemistry and structure. Thus, the rationale for the surface modification of biomaterials is straightforward: retain the key physical properties while modifying only the outermost surface to influence biointeraction. If surface modification is properly executed, the mechanical properties and functionality of the medical device will be unchanged, but the biocomparibility will be improved.
机译：正确设计，合成和制造生物材料将确保它们的表面分析具有适当的机械性能，耐用性和功能性。一些例子是应承受高压力的膝关节假体，应具有必需的渗透性特征的血液氧合膜以及在心脏瓣膜中应弯曲数百万个循环而不会失效的小叶。材料的整体结构决定了这些性能。另一方面，对生物材料的生物反应主要由其表面化学和结构决定。因此，生物材料表面改性的原理很简单：保留关键的物理特性，同时仅改性最外层表面以影响生物相互作用。如果适当地进行了表面改性，则医疗器械的机械性能和功能将保持不变，但生物相容性将得到改善。

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