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首页> 外文会议>International Conference on Monitoring of Toxic Chemical and Biomarkers >Exposure to propylene- and diethylene glycol ethers: analytical methods and biological monitoring
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Exposure to propylene- and diethylene glycol ethers: analytical methods and biological monitoring

机译：接触丙二醇和二甘醇醚：分析方法和生物监测

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摘要

Abstract: Twenty-two people involved with manufacturing brakehoses and exposed to the glycol ether 1-methoxypropanol-2, were assessed according to the external and internal exposure to this solvent. The elimination kinetics of 1- methoxypropanol-2 in man were studied and mean excretion half lives of approximately 4.4 h were found. On the basis of our results, we made a rough calculation for a future biological tolerance value for 1-methoxypropanol-2. On that basis we would expect that concentrations from 38 to 109 mg per liter of blood and 10 to 31 mg per liter of urine would correspond to the German maximum concentration at the workplace for 1-methoxypropanol-2 of 375 mg/m$+3$/. In addition, the analytical method which has been used for this purpose and its reliability criteria are shown.!4
机译：摘要：根据与该溶剂外部和内部的接触情况，评估了22名从事制动软管制造的人员，并对其暴露于乙二醇醚1-甲氧基丙醇-2中。研究了人体内1-甲氧基丙醇-2的清除动力学，发现平均排泄半衰期约为4.4 h。根据我们的结果，我们对1-甲氧基丙醇-2的未来生物耐受性值进行了粗略的计算。在此基础上，我们期望每升血液38至109毫克和每升尿10至31毫克的浓度将相当于德国工作场所1-甲氧基丙醇-2的最高浓度为375 mg / m $ + 3 $ /。此外，还显示了用于此目的的分析方法及其可靠性标准。！4

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