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Effect of maternal nutrition in the third trimester on fetal growth

机译:孕晚期孕妇营养对胎儿生长的影响

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To investigate the relationship between the dietary intake of normal pregnant women in Nanjing, China during the third trimester and fetal growth and birth weight. Methods: Nanjing women, in their 32 week, that visited the Prenatal Clinic at Nanjing Drum Tower Hospital, the Affiliated Hospital of Nanjing University Medical School, from January 2005 to April 2006 were enrolled for potential entry into this study. The exclusive cases were abnormal glucose challenge test, B type hepatic disease, cardiovascular, renal and/or other endocrine diseases’history. There were 799 women were included in this study. All participants were required to make a 24-hour dietary recall once prior to each of their scheduled visits during the 32nd, 34th, and 36th weeks of pregnancy respectively. At each of these three visits, their weights were recorded, and the dietary recall forms were collated by intake of various nutritional elements. Meanwhile they received ultrasound scan two times at about 28th weeks and 38th to measure fetal head circumference(HC), abdomen circumference(AC), femoral bone and humeral bone length(FL,HL) and biparietal diameter(BPD).Fetal birth weight was measured after delivery immediately. Result: Fetal birth weight tended to increase in pregnant women in relationship to fat intake. The proportion of energy derived from fat was related to fetal increased HC, AC and FL development in late pregnancy. HC increased 3.86mm(95% CI:0.56mm to6.93mm) and AC increased 2.27mm(95% CI:0.23mm to 4.45mm) as well as FL increase 1.35mm(0.26mm to 2.43mm) for each 1% increase in the proportion of energy derived from fat. FL increase 2mm(95% CI:0.15mm to 4.11mm) for each 100 mg increase with calcium intake ; BPD increased 0.53mm(95% CI:0.02mm to 1.47mm), 1.51mm(95% CI:0.12mm to 2.97mm), 1.79mm(95% CI:0.26mm to 3.88mm) and 2.48mm (95% CI:0.64mm to 5.03mm)for each 1mg increase in intake of Zn(P=0.05),VitE(P=0.016),VitB1(P=0.021),VitB2(P=0.033). Conclusion: Both the amount and density of fat intake in pregnant women was a significant factor in fetal birth weight, and increased fat intake during the third trimester can induce more macrosomia.
机译:目的探讨中国南京中期晚期孕妇的饮食摄入与胎儿生长和出生体重之间的关系。方法:选择2005年1月至2006年4月在南京鼓楼医院,南京大学医学院附属医院南京分院接受产前检查的妇女,为期32周。例外情况是异常葡萄糖激发试验,B型肝病,心血管,肾脏和/或其他内分泌疾病的病史。这项研究包括799名女性。在妊娠的第32周,第34周和第36周,所有参与者必须在每次安排的探访之前一次进行24小时饮食回想。在这三次访问中的每一次访问中,都要记录他们的体重,并通过摄入各种营养元素来整理饮食召回形式。同时他们分别在第28周和第38周接受了两次超声波扫描,以测量胎儿头围(HC),腹部围(AC),股骨和肱骨长度(FL,HL)和双顶径(BPD)。交货后立即测量。结果:与脂肪摄入有关,孕妇的胎儿出生体重倾向于增加。来自脂肪的能量比例与妊娠晚期胎儿HC,AC和FL发育增加有关。 HC增加3.86mm(95%CI:0.56mm至6.93mm),AC增加2.27mm(95%CI:0.23mm至4.45mm),FL增加1.35mm(0.26mm至2.43mm)来自脂肪的能量比例。随钙摄入量每增加100 mg,FL增加2mm(95%CI:0.15mm至4.11mm); BPD增加了0.53mm(95%CI:0.02mm至1.47mm),1.51mm(95%CI:0.12mm至2.97mm),1.79mm(95%CI:0.26mm至3.88mm)和2.48mm(95%CI)锌的摄入量每增加1mg则:0.64mm至5.03mm)(P = 0.05),VitE(P = 0.016),VitB1(P = 0.021),VitB2(P = 0.033)。结论:孕妇脂肪摄入量和密度都是影响胎儿出生体重的重要因素,妊娠晚期脂肪摄入增加可引起更多的巨大儿。

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