首页> 外文会议>“中、美食盐与健康”国际研讨会(International Workshop of Dietary Sodium and Human Health in China and the United States) >Simulated Mars-flight Sodium and Hypertension Study (SMASH Study): efficacy trial on the salt/blood pressure relationship
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Simulated Mars-flight Sodium and Hypertension Study (SMASH Study): efficacy trial on the salt/blood pressure relationship

机译:模拟火星飞行钠和高血压研究(SMASH研究):盐/血压关系的功效试验

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Although the evidence for a direct relationship between salt intake and blood pressure is widely accepted, there is controversy on whether this effect translates into increased incidence of cardiovascular disease in populations with high dietary salt consumption. This current controversy is not necessarily a dispassionate and balanced factual discussion in the search for a consensus of informed opinion, but has an emotional content. According to Beard and Stowasser, confusing the terms "efficacy" and "effectiveness" may invalidate important conclusions drawn after analysis of randomised, controlled studies (RCTs) on the interaction between salt and health. "Efficacy" refers to the impact of an intervention that is fully applied (e.g. during a controlled clinical trial), differing from "effectiveness" which refers to the impact in real world situations.
机译:尽管盐摄入量与血压之间存在直接关系的证据已被广泛接受,但在高盐饮食人群中,这种作用是否会导致心血管疾病的发病率增加,仍存在争议。当前的争论在寻求知情同意的过程中,不一定是一个冷淡而平衡的事实讨论,而是具有感性的内容。 Beard和Stowasser认为,混淆“功效”和“有效性”这两个术语可能会使对盐与健康之间相互作用的随机对照研究(RCT)进行分析后得出的重要结论无效。 “功效”是指完全实施的干预措施的影响(例如在受控临床试验期间),与“有效性”不同,后者是指在现实情况下的影响。

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