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A multi-compartment computer simulation for analysis of fluid resuscitation following hemorrhagic shock

机译:多室计算机模拟,用于分析失血性休克后的液体复苏

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A multi-compartment model of the cardiovascular system was designed to address questions regarding myocardial oxygen balance during fluid resuscitation. The model includes nonlinear compliant chambers of the systemic and pulmonary interstitial compartments. It also includes calculations of hematocrit and colloid osmotic pressure and flows between the interstitium and the vascular chambers. The computer simulation of the model demonstrates that in addition to pulmonary and systemic edema, cardiac oxygen balance is an important factor which must be considered during fluid therapy. The simulation also suggests that limiting the rate of infusion reduces this risk.
机译:设计了心血管系统的多室模型,以解决有关液体复苏过程中心肌氧平衡的问题。该模型包括全身和肺间质隔室的非线性顺应性室。它还包括血细胞比容和胶体渗透压以及间质与血管腔之间的流量的计算。该模型的计算机模拟表明,除了肺部和全身性水肿外,心脏氧平衡也是重要的因素,在进行液体治疗时必须予以考虑。模拟还表明,限制输液速度可以降低这种风险。

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