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首页> 外文会议>International conference on environmental biotechnology and materials engineering;EBME 2011 >The Immunomodulating Effect of Polysaccharides Purified from Pholiota adipose
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The Immunomodulating Effect of Polysaccharides Purified from Pholiota adipose

机译：磷脂脂肪多糖的免疫调节作用。

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This study was designed to investigate the immunomodulating effect of polysaccharides purified from the fruit body of Pholiota adipose(PFBP). PFBP were extracted in 90°C water bath and precipitated with 90％ ethanol. PFBP were orally administered at different dose to three different doses were administered to the normal group, NS group and the model group. The immunomodulating effect of PFBP was evaluated by measuring its effects on the weights of spleen and liver, delayed type hypersensitivity(DTH) response, the hemolysin level in serum and carbon expurgation level. Polysaccharide content purified from fruit body of Pholiota adipose was up to 72.88％. PFBP administered at different doses significantly improved the weights of the mouse's spleen and live, as well as the level of carbon expurgation. Administered polysaccharides also had positive effect on DTH response and the hemolysin level in serum. These results suggest that PFBP may have immunomodulating potential for cylophosphamide.
机译：本研究旨在研究从大豆脂肪（PFBP）子实体中纯化的多糖的免疫调节作用。 PFBP在90°C水浴中萃取，并用90％乙醇沉淀。正常组，NS组和模型组分别以不同剂量口服PFBP和三种不同剂量。通过测量PFBP对脾脏和肝脏重量，迟发型超敏反应（DTH）反应，血清中的溶血素水平和碳清除水平的影响，评估其的免疫调节作用。从百里香脂肪子实体中纯化得到的多糖含量高达72.88％。以不同剂量给药的PFBP可以显着改善小鼠脾脏和活体的重量以及碳清除水平。给予的多糖对DTH反应和血清中的溶血素水平也具有积极作用。这些结果表明PFBP可能具有环磷酰胺的免疫调节潜力。

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