• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文会议>2011 4th International Conference on Biomedical Engineering and Informatics >Prevalence and charaterization of carbapenem-resistant Pseudomonas aeruginosa carrying metallo-β-lactamases at different wards
【24h】

Prevalence and charaterization of carbapenem-resistant Pseudomonas aeruginosa carrying metallo-β-lactamases at different wards

机译：在不同病区携带抗金属蛋白酶β-内酰胺酶的耐碳青霉烯的铜绿假单胞菌的流行和特征

获取原文
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

This study was conducted to investigate the molecular occurrence and dissemination of Pseudomonas aeruginosa producing MBLs recovered from the different wards in the affiliated hospital, Jilin. Antibiotic susceptibility test was determined using standard agar diffusion in conjunction with MBL screening methods. Plasmid profiles and pulsed-field gel electrophoresis were used to study the relatedness of isolates. The total of 120 were isolated from three wards and 89 strains (74.8%) produced MBLs, the number of 31 strains (25.2%) didn't produce MBLs. All MBLs isolates showed identical antimicrobial susceptibility profiles. Among P. aeruginosa producing MBLs, 79 strains (88.9%) were positive for blaVIM-2 gene, 12 strains (11.1%) contained blaIMP-3 gene, which were located on transferable plasmids with class 1 integron. All MBLs isolates were closely related by PFGE and plasmid analysis. This study confirmed the potential risk of dissemination of carbapenem-resistant Pseudomonas aeruginosa with inter-and intrahospital clonal transfer of patients.
机译：这项研究旨在调查从附属医院吉林省不同病房回收的产铜绿假单胞菌MBL的分子发生和传播情况。使用标准琼脂扩散结合MBL筛选方法确定抗生素敏感性试验。质粒图谱和脉冲场凝胶电泳用于研究分离株的相关性。从3个病房中分离出120个菌株，其中89个菌株（74.8％）产生了MBL，31个菌株（25.2％）没有产生MBL。所有MBLs分离物均显示出相同的抗药性。在产铜绿假单胞菌的MBLs中，bla VIM-2 基因呈阳性的菌株有79株（88.9％），含有bla IMP-3 基因的12株（11.1％）为阳性。它们位于具有1类整联子的可转移质粒上。通过PFGE和质粒分析，所有MBLs分离物都密切相关。这项研究证实了散发耐碳青霉烯的铜绿假单胞菌可能会导致患者间和医院内的克隆转移。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号