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FMRI ANALYSIS THROUGH BAYESIAN VARIABLE SELECTION WITH A SPATIAL PRIOR

机译:通过使用空间的贝叶斯变量选择FMRI分析

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This paper presents a novel spatial Bayesian method for simultaneous activation detection and hemodynamic response function (HRF) estimation of functional magnetic resonance imaging (fMRI) data. A Bayesian variable selection approach is used to induce shrinkage and sparsity, with a spatial prior on latent variables representing activated hemodynamic response components. Then, the activation map is generated from the full spectrum of posterior inference constructed through a Markov chain Monte Carlo scheme, and HRFs at different voxels are estimated non-parametrically with information pooling from neighboring voxels. By integrating functional activation detection and HRFs estimation in a unified framework, our method is more robust to noise and less sensitive to model mis-specification.
机译:本文介绍了一种新型空间贝叶斯方法,用于同时激活检测和血液动力响应函数(HRF)估计功能磁共振成像(FMRI)数据的估计。贝叶斯变量选择方法用于诱导收缩和稀疏性,在潜在变量上具有表示激活的血液动力学响应组件的空间。然后,从通过Markov链蒙特卡罗方案构成的全谱产生激活图,并且在不同体素处的HRF与来自相邻体素的信息汇率估计。通过在统一的框架中积分功能激活检测和HRFS估计,我们的方法对噪声更加坚固,对模型错误规范不太敏感。

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