• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文会议>International work-conference on bioinformatics and biomedical engineering >Radiofrequency Ablation for Treating Chronic Pain of Bones: Effects of Nerve Locations
【24h】

Radiofrequency Ablation for Treating Chronic Pain of Bones: Effects of Nerve Locations

机译：射频消融治疗慢性骨痛：神经部位的影响

获取原文
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

The present study aims at evaluating the effects of target nerve location from the bone tissue during continuous radiofrequency ablation (RFA) for chronic pain relief. A generalized three-dimensional heterogeneous computational model comprising of muscle, bone and target nerve has been considered. The continuous RFA has been performed through the monopolar needle electrode placed parallel to the target nerve. Finite-element-based coupled thermo-electric analysis has been conducted to predict the electric field and temperature distributions as well as the lesion volume attained during continuous RFA application. The quasi-static approximation of the Maxwell's equations has been used to compute the electric field distribution and the Pennes bioheat equation has been used to model the heat transfer phenomenon during RFA of the target nerve. The electrical and thermo-physical properties considered in the present numerical study have been acquired from the well-characterized values available in the literature. The protocol of the RFA procedure has been adopted from the United States Food and Drug Administration (FDA) approved commercial devices available in the market and reported in the previous clinical studies. Temperature-dependent electrical conductivity along with the piecewise model of blood perfusion have been considered to correlate with the in-vivo scenarios. The numerical simulation results, presented in this work, reveal a strong dependence of lesion volume on the target nerve location from the considered bone. It is expected that the findings of this study would assist in providing a priori critical information to the clinical practitioners for enhancing the success rate of continuous RFA technique in addressing the chronic pain problems of bones.
机译：本研究旨在评估在连续射频消融（RFA）期间从骨组织中靶神经位置对慢性疼痛的缓解作用。已经考虑了由肌肉，骨骼和目标神经组成的广义三维异构计算模型。通过平行于目标神经放置的单极针状电极进行连续RFA。已经进行了基于有限元的耦合热电分析，以预测连续RFA应用期间的电场和温度分布以及病变体积。麦克斯韦方程的准静态逼近已用于计算电场分布，潘尼斯生物热方程已用于模拟目标神经RFA期间的热传递现象。本数值研究中考虑的电学和热物理性质已经从文献中可获得的充分表征的值中获得。 RFA程序的协议已从美国食品和药物管理局（FDA）批准的市售商用设备中采用，并在先前的临床研究中进行了报道。与温度有关的电导率以及血液灌注的分段模型已被认为与体内情况相关。在这项工作中提出的数值模拟结果表明，病变体积对所考虑的骨骼对目标神经位置的强烈依赖性。预期该研究的结果将有助于向临床从业者提供先验的关键信息，以提高连续RFA技术解决骨骼慢性疼痛问题的成功率。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号