COLLAGEN CONTENT AND STIFFNESS AFFECT THE BIOMECHANICAL RESPONSE OF COLLAGEN GELS TO ACUPUNCTURE IN VITRO

机译：胶原蛋白含量和硬度影响胶原蛋白对针刺的生物力学响应

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Acupuncture is an ancient therapy that has been clinically proven for treating pain and nausea, though by unknown mechanisms. Recent in vivo and ex vivo studies demonstrate that acupuncture generates changes in the local tissue biomechanical environment, which may have been overlooked in previous neurophysiological studies.During traditional acupuncture therapy, fine needles arc inserted into specific points on the body and manipulated, typically in the form of needle rotation. Recent studies have shown that subcutaneous connective tissue winds around the needle during rotation, and that fibroblasts within the connective tissue arc stimulated to change their morphology and remodel their cytoskcleton by the altered tissue mechanics.

机译：针灸是一种古老的疗法，尽管其机理尚不清楚，但已被临床证明可用于治疗疼痛和恶心。最近的体内和离体研究表明，针灸会在局部组织生物力学环境中产生变化，这在以前的神经生理学研究中可能已被忽略。在传统的针灸治疗过程中，通常将细针插入身体的特定部位并进行操作，通常以旋转针的形式进行。最近的研究表明，皮下结缔组织在旋转过程中缠绕在针头周围，结缔组织内的成纤维细胞受组织力学改变的刺激而改变其形态并重塑其细胞骨架。

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《ASME summer bioengineering conference;SBC2008》|2009年|829-830|共2页
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MARGARET JULIAS; LOWELL T. EDGAR; DAVID I. SHREIBER; HELEN M. BUETTNER;
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2. Osteoblast responses to collagen-PVA bioartificial polymers in vitro: the effects of cross-linking method and collagen content. [J] . Scotchford CA, Cascone MG, Downes S, Biomaterials . 1998,第1a3期

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3. Fibroblast-seeded collagen gels in response to dynamic equibiaxial mechanical stimuli: A biomechanical study [J] . Lee Pei-Yuan, Liu Yen-Ching, Wang Mei-Xuan, Journal of Biomechanics . 2018,第期

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4. COLLAGEN CONTENT AND STIFFNESS AFFECT THE BIOMECHANICAL RESPONSE OF COLLAGEN GELS TO ACUPUNCTURE IN VITRO [C] . ASME bioengineering conference . 2009

机译：胶原蛋白含量和刚度影响胶原凝胶对体外针灸的生物力学响应
5. Nearby fibroblasts' response to multiple acupuncture needle revolutions on fibroblast populated collagen gels [D] . Chu, Ka Po 2011

机译：邻近成纤维细胞对成纤维细胞填充胶原凝胶多次针刺针旋转的反应
6. Muscle-derived stem cell seeded fibrin gel interposition producesgreater tendon strength and stiffness than collagen gel in vitro [O] . Y. Ozasa, A. Gingery, P. C. Amadio -1

机译：肌肉来源的干细胞接种纤维蛋白凝胶插入产生在体外比胶原蛋白凝胶具有更大的肌腱强度和刚度
7. Advanced glycation end-products reduce collagen molecular sliding to affect collagen fibril damage mechanisms but not stiffness [O] . Fessel, Gion, Li, Yufei, Diederich, Vincent, 2014

机译：先进的糖基化终产物可减少胶原蛋白分子的滑动，从而影响胶原蛋白原纤维的损伤机制，但不影响硬度

COLLAGEN CONTENT AND STIFFNESS AFFECT THE BIOMECHANICAL RESPONSE OF COLLAGEN GELS TO ACUPUNCTURE IN VITRO

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