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首页> 外文会议>ASME summer bioengineering conference;SBC2008 >REGIONAL CARTILAGE THINNING OCCURS FIRST IN THE WALKING WEIGHT BEARING REGIONS OF THE FEMUR IN MEDIAL COMPARTMENT KNEE OSTEOARTHRITIS
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REGIONAL CARTILAGE THINNING OCCURS FIRST IN THE WALKING WEIGHT BEARING REGIONS OF THE FEMUR IN MEDIAL COMPARTMENT KNEE OSTEOARTHRITIS

机译：膝关节骨关节炎患者股骨的步行承重区域中首先出现的区域性软骨变薄

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摘要

Osteoarthritis (OA) of the knee affects an estimated 20-40% of individuals over the age of 65, and is nearly 10 times more common in the medial compartment than the lateral compartment. Plain radiography measurements using the Kellgren and Lawrence (KL) scale have been the gold standard for diagnosis of knee osteoarthritis. However, for new treatment interventions for medial compartment knee OA such as load modifying footwear, it would be important to know if the disease-related cartilage loss in the medial compartment occurs initially and predominantly in regions that are weight bearing during walking.
机译：膝盖骨关节炎（OA）估计会影响65岁以上的20-40％的个体，并且在内侧腔室中的发病率比外侧腔室高出近10倍。使用Kellgren and Lawrence（KL）量表的X射线平片测量已成为诊断膝骨关节炎的金标准。但是，对于内侧隔膝OA的新治疗干预措施（例如，改变负重的鞋类），重要的是要知道内侧隔室中与疾病相关的软骨损失是否最初且主要发生在步行过程中负重的区域。

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