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Evaluation of silicon extract from leaves of Phyllostachys edulis for topical antiosteoporosis activity

机译:从Phyllostachys Edulis叶片评估局部抗软疏松症活性的硅提取物

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This study was intended to investigate the assimilation and the effect of BS on bone loss in ovariectomized rats. 100 Adult female SD rats were randomly divided into 5 groups. One group was sham operated and ovariectomy rats were performed in other 4 groups: three of which were respectively supplemented with 1.0 mg BS, 1.0 mg estradiol, 150.0 mg Ca/kg BW/day and other rats were model controls. Urine was collected in metabolic cages after 1 month and rats were sacrificed after 3 months. Bone density (BMD) was analyzed by Dual Energy X-Ray Absorptiometry and Si concentration was measured by Electrothermal Atomic Absorption Spectrometry with Zeeman background correction. The results showed that BS supplementation increased significantly the femoral and Lumbar BMD (H1: +8.59%, H2: +9.58%, HT: +9.38%, L: +13.48%, BSG vs MCG, p<0.01). The present results suggest that BS may have a beneficial action on bone health.
机译:本研究旨在探讨BS对卵巢切除大鼠骨质损失的同化及其影响。 100只成年女性SD大鼠随机分为5组。一组是假手术,在其他4组中进行卵巢切除大鼠:其中三个分别用1.0mg Bs,1.0mg雌二醇,150.0mg Ca / kg Bw / Diat和其他大鼠进行模型对照。在1个月后在代谢笼中收集尿液,在3个月后处死大鼠。通过双能量X射线吸收测定法分析骨密度(BMD),通过电热原子吸收光谱法测量Si浓度与塞曼背景校正。结果表明,BS补充显着增加了股骨和腰部BMD(H1:+ 8.59%,H2:+ 9.58%,HT:+ 9.38%,L:+ 13.48%,BSG VS MCG,P <0.01)。本结果表明BS可能对骨骼健康有益的作用。

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