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首页> 外文会议>2011 International Conference on Human Health and Biomedical Engineering >Deferring senile effect of polysaccharides from Angelica and Astragalus on aging mice
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Deferring senile effect of polysaccharides from Angelica and Astragalus on aging mice

机译：延缓当归和黄芪多糖对衰老小鼠的衰老作用

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Angelica and Astragalus, Chinese herbal medicine, are used as immunostimulants for enriching the blood, anti-tumor and antioxidation effects. However, the synergistic mechanisms of antioxidant effect have long been the object of intensive study. We investigated the deferring senile effect of AAP on aging mice by determination of the contents of monoamine oxidase (MAO) in brain, hydroxyproline (Hyp) in skin, hydrogen peroxide (H2O2) in serum, glutathione peroxidase (GSH-PX) and xanthine oxidase (XOD) in liver tissue and immunity organs index. The obtained results showed that AAP decreased significantly the content of MAO and H2O2, and enhanced the concentrations of Hyp, GSH-PX and XOD in vivo. No significant differences were found when compared with those of vitamin E. Additionally, AAP could increase immunity organs index. These results demonstrated that AAP had significant deferring senile effect on the aging mice. These changes may be the important mechanisms to prevent mice from aging.
机译：当归和黄芪作为中草药被用作免疫刺激剂，以丰富血液，抗肿瘤和抗氧化作用。然而，抗氧化剂作用的协同机制长期以来一直是深入研究的目的。我们通过测定大脑中单胺氧化酶（MAO），皮肤中的羟脯氨酸（Hyp），过氧化氢（H 2 O 2 < / inf>），肝组织中的谷胱甘肽过氧化物酶（GSH-PX）和黄嘌呤氧化酶（XOD）和免疫器官指数。结果表明，AAP能显着降低体内MAO和H 2 O 2 的含量，并能提高Hyp，GSH-PX和XOD的含量。与维生素E相比，没有发现显着差异。此外，AAP可以增加免疫器官指数。这些结果表明AAP对衰老小鼠具有显着的延缓衰老作用。这些变化可能是防止小鼠衰老的重要机制。

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