首页> 外文会议>ASME summer bioengineering conference;SBC2011 >CELL-MATRIX INTERACTIONS MODULATE MESENCHYMAL STEM CELL RESPONSE TO DYNAMIC COMPRESSION
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CELL-MATRIX INTERACTIONS MODULATE MESENCHYMAL STEM CELL RESPONSE TO DYNAMIC COMPRESSION

机译:细胞-基质相互作用调节间充质干细胞对动态压缩的反应

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Unconfined cyclic compressive loading has been shown to promote the chondrogenic differentiation of agarose encapsulated mesenchymal stem cells (MSCs) in the absence of chondrogenic growth factors [1, 2], However, in general robust chondrogenesis has not been reported as a result of mechanical stimulation alone; with biochemical stimulation through TGF-β supplementation yielding a more potent pro-chondrogenic effect [2, 3].
机译:在无软骨生成生长因子的情况下,无限制的循环压缩负荷已显示可促进琼脂糖包裹的间充质干细胞(MSC)的软骨生成分化[1、2],但是,一般而言,尚未报道由于机械刺激而产生强健的软骨生成独自的;通过添加TGF-β的生化刺激产生更强的促软骨形成作用[2,3]。

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