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首页> 外文会议>International conference on human-computer interaction;International conference on augmented cognition >Time Dependent Effects of Transcranial Direct Current Stimulation and Caffeine on Vigilance Performance During Extended Wakefulness
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Time Dependent Effects of Transcranial Direct Current Stimulation and Caffeine on Vigilance Performance During Extended Wakefulness

机译：经颅直流电刺激和咖啡因对长时间清醒期间警觉性能的时间依赖性影响

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Background: Previously, we found that transcranial direct current stimulation (tDCS) preserved vigilance performance approximately twice as well and three times as long as caffeine during a period of extended wakefulness. Vigilance performance often declines linearly over the period of watch, but in our previous study the performance trends over the period of watch were not analyzed. Hence, it was not known whether the intervention applied reduced the vigilance decrement, or simply shifted the performance to a higher mean value while maintaining a similar slope. Objective: Our objective was to evaluate the time-dependent effects (within each period of watch) of anodal transcranial direct current stimulation (tDCS) applied to the pre-frontal cortex at 2 mA for 30 min. We then compared these results to those of caffeine as well as the effects of both interventions on arousal. Methods: The period of watch was segregated into equal time segments and target identification accuracy was averaged across subjects in each group. These values were used in an analysis of covariance (separately for each session) as the dependent variable. Factors were group and subject nested in group. Results: The results indicated there is not a significant difference in slope (i.e. vigilance decrement) between the treatment conditions (tDCS, caffeine, and sham) within each period of watch. However, as reported previously, there was a significant difference in mean change from baseline between the treatment conditions. Conclusion: Our data suggests that tDCS does not prevent the vigilance decrement within the period of watch. Rather, it shifts performance to higher mean values by a scalar multiple while maintaining a similar slope.
机译：背景：以前，我们发现经颅直流电刺激（tDCS）在长时间的清醒期间保持的警觉性大约是咖啡因的两倍和三倍。监视期间的警戒性能通常会线性下降，但是在我们之前的研究中，未分析监视期间的性能趋势。因此，不知道所采用的干预措施是减少警惕性下降，还是只是在保持相似斜率的同时将性能提高到更高的平均值。目的：我们的目的是评估在2 mA的条件下对前额叶皮层施加30分钟的经颅经颅直流电刺激（tDCS）的时间依赖性效应（在每个观察周期内）。然后，我们将这些结果与咖啡因的结果以及两种干预对唤醒的影响进行了比较。方法：将观察期分为相等的时间段，并在每组受试者中平均目标识别准确性。这些值用作协变量的协方差分析（每个阶段分别使用）。将因素分为组，将主题嵌套在组中。结果：结果表明在每个观察期间，治疗条件（tDCS，咖啡因和假手术）之间的斜率（即警惕性降低）没有显着差异。但是，如前所述，治疗条件之间的平均变化与基线之间存在显着差异。结论：我们的数据表明，tDCS不能防止在观察期间内警觉性下降。相反，它将标量倍数转换为更高的平均值，同时保持相似的斜率。

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