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首页> 外文会议>IEEE Engineering in Medicine and Biology Annual Conference >Response of simulataneously recorded cortical neurons to perturbations in ARM trajectory
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Response of simulataneously recorded cortical neurons to perturbations in ARM trajectory

机译：将模拟记录皮质神经元对臂轨迹扰动的反应

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摘要

Cortical neural prostheses may someday be used to augment or restore lost motor functions by deriving movement commands from neural activity recorded in the brain. Many studies have identified relationships between the discharge patterns ofcortical neurons and arm movement parameters (e.g. direction and force). We are currently investigating these relationships in simultaneously recorded cortical neurons to generate a movement command in real4ime. A perturbation paradigm has beenimplemented to study changes in cortical activity as the monkey responds and adapts to a perturbation in trajectory. Over 40 neurons were recorded simultaneously over a 2-week period. Distinct and stable cortical responses (to movement and perturbation)were observed across the two weeks of trials.
机译：皮质神经假肢可能有一天可以通过从大脑中记录的神经活动导出运动命令来增加或恢复失去的电动机功能。许多研究已经鉴定了触发性神经元和臂运动参数（例如方向和力）之间的关系。我们目前正在调查同时记录皮质神经元的这些关系，以真实地生成运动命令。由于猴子响应并适应轨迹扰动，扰动范例已经掌握了研究皮层活动的变化。在2周的时间内同时记录超过40个神经元。在两周的试验中观察到不同且稳定的皮质反应（对运动和扰动）。

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