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首页> 外文会议>International Symposium on Blood Transfusion >CLOSING THE WINDOW OF EARLY HIV INFECTION BY INCORPORATION OF HIV P24 Ag DETECTION IN AN ANTI-HIV-1/-2/-O ASSAY: VIRONOSTIKA~R HIV UNIFORM H Ag/Ab
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CLOSING THE WINDOW OF EARLY HIV INFECTION BY INCORPORATION OF HIV P24 Ag DETECTION IN AN ANTI-HIV-1/-2/-O ASSAY: VIRONOSTIKA~R HIV UNIFORM H Ag/Ab

机译：通过在抗HIV-1 / -2 / -O测定中掺入HIV P24 AG检测来关闭早期HIV感染的窗口：VIRONOUTIKA〜R HIV均匀H AG / AB

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Historically, the performance of anti-HIV assays over the last 10 years has shown great improvements in sensitivity and specificity. Relatively insensitive viral lysate based assays, applied in an indirect assay format were replaced by sensitive tests based on highly purified HIV specific antigens, which are usually viral or recombinant proteins or synthetic peptides. These antigen combinations are usually applied in a sandwich assay format. By using these sensitive 3rd generation anti-HIV sandwich assays in the bloodbanking environment, the risk of releasing a HIV positive sample for transfusion lias been greatly lowered. Some time ago Organon Teknika has updated its HIV Uni-Form II assay with HIV-1 group O antigen for optimal HIV subtype detection, resulting in the Vironostika~R HIV Uni-Form llplus O assay [1,2].
机译：从历史上看，过去10年来抗HIV测定的表现表现出敏感性和特异性的巨大改善。基于不敏感的病毒裂解物，以间接测定形式施加的基于间接测定形式的测定是基于高度纯化的HIV特异性抗原的敏感试验代替，这通常是病毒或重组蛋白或合成肽。这些抗原组合通常以夹层测定形式施加。通过使用这些敏感的第3代抗HIV夹层测定在血橇环境中，释放用于输血leas的HIV阳性样品的风险大大降低。在某种句时候，Consoron Teknika已经用HIV-1组抗原更新了HIV Uni-Form II测定，以获得最佳的HIV亚型检测，导致vironostika〜R HIV Uni-Form LLPlus O测定[1,2]。

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