• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文会议>Annual Veterinary Medical Forum >ECHO prognostic indicators for DCM
【24h】

ECHO prognostic indicators for DCM

机译：DCM的回声预后指标

获取原文
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Idiopathic dilated cardiomyopathy (DCM) is defined as a cardiac muscle disease of unknown etiology and is characterized by enlargement of the cardiac chambers and severe systolic dysfunction. The disease represents one of the most common acquired cardiovascular diseases of dogs with a reported prevalence of 0.5 percent, and although it has been identified with increasing frequency in medium-sized breeds, it remains primarily a disease of large and giant purebreed dogs. The natural history of DCM has been better studied in Doberman Pinchers, Irish Wolfhound, and Great Danes who have a long period during which they have myocardial failure but not clinical signs (Occult DCM). The disease however progresses inevitably into congestive heart failure (CHF) if this progression is not preempted by sudden death. Once dogs affected show signs of CHF the short and long-term prognosis is poor despite adequate medical therapy. In people indicators predicting poor prognosis in patients with left ventricular dysfunction and CHF include age, etiology, left ventricular ejection fraction (EF), functional class, exercise capacity, pulmonary arterial pressure, increased level of plasma norepinephrine, and hyponatremia. In dogs few studies have been conducted to characterize prognostic indicators in patients with DCM, with pulmonary edema, pleural effusion, age, dyspnea, ascites, atrial fibrillation and bilateral CHF, representing the best independent parameters associated with significantly shorter survival times.Since CHF secondary to systolic dysfunction as happens in DCM is associated with substantial reduction in life expectancy, it would be important to be able to stratify patients with congestive heart failure according to groups with the highest risk for early death because aggressive medical treatment could be specifically applied to this population. Moreover, ideally, changes in prognostic variables after therapy should also indicate for a longer or shorter life expectancy.
机译：特发性扩张的心肌病（DCM）被定义为未知病因的心肌疾病，其特征在于心脏室的扩大和严重的收缩功能障碍。该疾病代表了禽类最常见的血管疾病之一，据报道的患病率为0.5％，尽管已经鉴定了中等品种的频率越来越多，但它仍然是大型和巨大的纯种狗的疾病。 DCM的自然历史在Doberman Cinchers，Irish Wolfhound和Great Danes中获得了更长的时间，他们具有长期的丹麦人，他们具有心肌失效但不是临床迹象（隐匿性DCM）。然而，如果这种进展不被猝死抢占，这种疾病是不可避免地进入充血性心力衰竭（CHF）。一旦狗受到影响，表现出CHF的迹象，尽管有足够的医疗治疗，但短期和长期预后差。在人们的指标中预测左心室功能障碍患者预后差的预后包括年龄，病因，左心室喷射分数（EF），功能阶级，运动能力，肺动脉压，血浆去甲肾上腺素水平和低钠血症。在狗中，已经进行了一些研究，以表征DCM患者的预后指标，患有肺水肿，胸腔积液，年龄，呼吸困难，腹水，心房颤动和双侧CHF，代表与较短的生存时间相关的最佳独立参数。SINCE CHF中学对于收缩功能障碍，因为DCM发生在预期寿命的大幅减少相关，能够根据早期死亡风险最高的群体来分析充血性心力衰竭的患者是很重要的，因为侵略性的医疗可以专门应用于此人口。此外，理想情况下，治疗后预后变量的变化也应该表明寿命更长或更短。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号