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The effect of incorporating drugs on the free radical polymerization reaction of PEM/THFM and vice versa.

机译:将药物掺入PEM / THFM自由基聚合反应的效果,反之亦然。

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摘要

Controlled drug delivery in dentistry has caused considerable interest in recent years. Existing mateirals include varnishes containing either chlorhexidine or miconazole for application to dentures, others include appliances to treat candidal infections and the so-called perio-chips, consisting of gelatine containing metronidazole, for the treatment of acute gingivitis.~1 Fluoride releasing resins, apart from the well established glass ionomer cements, are used to inhibit dental caries~2. the concept has been extended to composite filling materials~3 and to dental delivery systems.~4 Patel et al have also shown that the poly(ethyl methacrylate)/tetrahydrofurfuryl methacrylate (PEM/THFM) system to have superior release properties of gentamicin compared to conventional bone coments.
机译:牙科控制的药物递送近年来造成了相当大的兴趣。现有的配合物包括含有氯己定或咪康唑的清漆,用于申请假牙,其他包括用于治疗候选感染和所谓的Perio-chips的器具,其由含有甲硝唑的明胶组成,用于治疗急性牙龈炎。〜1氟化物释放树脂,分开从建立的玻璃离子晶体水泥,用于抑制龋齿〜2。该概念已扩展到复合填充材料〜3和牙科递送系统。〜4 Patel等,还表明,与庆大蛋白的甲基丙烯酸甲酯(PEM / THFM)/四氢呋喃酯(PEM / THFM)系统相比具有优异的雷菊酯释放性能。常规骨骼。

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