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Self-organizing phenomena induced by LLLT in Henoch-Schonlein purpura

机译：LLLT在Henoch-Schonlein Purpura诱导的自组织现象

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Henoch-Schoenlein purpura is characterized by vasculitis of small vessels, particularly those of the skin, gastrointestinal tract, and kidney. Patients have characteristic purpuric skin rash plus all or some of the following: migratory polyarthralgias or polyarthritis, colicky abdominal pain, nephritis. Because until now there is no satisfactory treatment, we applied low level laser therapy (LLLT) in order to compare it with the classical therapy. Twenty-three children (2-15 years of age) have been treated at debut of the disease. They were randomly divided: group A (11 children) received LLLT; group B (12 children) was administrated classical therapy. Two GaAlAs diode lasers (670 nm and 830 nm) were used. The density of energy (4-8 J/cm~2), irradiating frequency (2.4 Hz) was applied one session daily, using scanning technique under a special treatment protocol on cutaneous purpuric areas (20 sessions). The best results were obtained in laser group. Despite the complex medication, some patients from group B fell back into the former state after apparent improvement, and two children developed nephritis. The results could be explained by self-organization. LLLT is acting as a trigger factor causing certain systemic effects through circulating blood and a response of the entire immune system, by way of synergetic mechanisms.
机译：Henoch-schoenlein purpura的特征在于小血管的血管炎，特别是皮肤，胃肠道和肾脏的血管炎。患者有特色的紫癜皮疹加上以下全部或部分：迁移的聚亚弧度或多甲状腺炎，肠道腹痛，肾炎。因为到目前为止没有令人满意的治疗，我们施加了低水平的激光治疗（LLLT），以便将其与典型治疗进行比较。在疾病首次亮相对二十三名儿童（2-15岁）被治疗。他们是随机分开的：A组（11名儿童）收到LLLT; B组（12名儿童）受到典型治疗。使用两个Gaalas二极管激光器（670nm和830nm）。能量密度（4-8 j / cm〜2），照射频率（2.4 hz）每天应用一项会议，在皮肤紫癜区域的特殊治疗方案下使用扫描技术（20次会议）。在激光组中获得了最佳结果。尽管药物复杂，但B组的一些患者在表观改善后倒入前状态，两名儿童发育了肾炎。结果可以通过自组织解释。通过协同机制，LLLT作为引起某种全身效应的触发因子，导致全身效应和整个免疫系统的响应。

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