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Commentary on Improving Outcomes of Low-Birthweight Infants

机译:改善低孕产婴幼儿结果的评论

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Brain of the fetus undergoes remarkable physical and functional development. Brain weight increases from 150 to 400 g in last trimester and it again doubles in weight in the first 6 months of life. At 6 months, it reaches approximately two thirds of adult brain weight [1]. Low birthweight includes babies born with birthweight <2,500 g. These babies may be preterm appropriate for gestational age (AGA), term small for gestational age (SGA) or preterm SGA. Intrauterine growth-restricted (IUGR) babies have a substantially higher rate of minor handicaps that include broad spectrum of cognitive and learning disorders. The latter includes deficits in attention, memory processing and verbal abilities. A 6- to 8-point intelligence quotient decrement has been documented in term IUGR babies. Preterm babies who are IUGR as compared to their AGA counterparts are at higher risk of poor neurodevelopmental outcomes [2]. Nutritional intervention in postnatal period is documented as one of the strategies to improve neurodevelopmental outcome in these babies.
机译:胎儿的脑部经历了显着的身体和功能发展。最后三个月的脑重量从150到400克增加,它在生命的前6个月内再次重量。在6个月,它达到大约三分之二的成人脑体重[1]。低出生体重包括出生的婴儿<2,500克。这些婴儿可能是适合于妊娠龄(AGA)的早产,妊娠期术语小(SGA)或早产SGA。宫内生长受限制(IUGR)婴儿具有基本上更高的轻微障碍率,包括广泛的认知和学习障碍。后者包括关注,内存处理和口头能力的缺陷。在IUGR婴儿的术语中,已经记录了6至8点的智能商量。与其AGA同行相比,是IUGR的早产儿是较差的神经发育成果的风险较高[2]。产后期间的营养干预被记录为改善这些婴儿的神经发育结果的策略之一。

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