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ICD Patients: What Is the Efficacy of Early Actuation of Atrial ATP Therapies in Atrial Fibrillation Termination?

机译:ICD患者:早期发生心房颤动终止的心房ATP疗法的疗效是什么?

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Atrial fibrillation (AF)/atrial tachycardia (AT) is one of the most common arrhythmias. It has been reported that a relevant percentage of patients implanted with implantable cardioverter defibrillators (ICDs) have atrial tachyarrhyth-mias at the time of implant [1]. One of the most interesting results of the recently available atrial-ventricular dual-chamber ICD clinical investigations is the significantly high success rate of automatic atrial anti-tachy-pacing (ATP) therapies in AF/AT termination: atrial bursts, ramps and high frequency bursts (50 Hz bursts) successfully terminated 68% of the device-detected atrial episodes [2-4] in patients with an indication for ventricular ICD. In spite of the considerably high AF/AT termination rate, no significant reduction was observed in terms of AF/AT burden or mean duration of AF/AT episodes. A possible explanation of these surprising data may relate to no limit being imposed on the ATP intervention delay from the episode onset.
机译:心房颤动(AF)/心房心动过速(AT)是最常见的心律失常之一。据报道,植入可植入心脏去纤维除颤器(ICDS)的患者的相关百分比在植入时具有心房Tachyarlyth-Mias [1]。最近可用的心房 - 心室双室ICD临床研究中最有趣的结果之一是AF /终止中的自动心房抗快节(ATP)疗法的显着高度成功率:心房突发,斜坡和高频突发(50 Hz突发)成功终止了68%的设备检测的心房剧集[2-4],患者患有心室ICD。尽管终止率相当高,但在AF /处于AF / AF / AT的持续时间内没有观察到显着减少。对这些令人惊讶的数据的可能解释可以涉及来自集发作开始的ATP干预延迟的无限制。

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