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Clinical aspects and pathology of primary cutaneous B-cell lymphomas.

机译:初级皮肤B细胞淋巴瘤的临床方面和病理学。

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Primary cutaneous B-cell lymphomas (pCBCL) occur more frequently than generally believed. The most important subtypes are: marginal zone B-cell lymphoma/immunocytoma, follicle center-cell lymphoma and large B-cell lymphoma of the leg. A correct diagnosis can be rendered only in the context of knowledge of the clinical findings. Progress in terms of classification and biology is associated with the application of modern techniques including immunohistology and laser beam microdissection followed by molecular analysis. Future definitions of pCBCL will be based on their molecular abnormalities and their etiology and pathogenesis. Awareness of the special clinical behavior of pCBCL should prevent unnecessarily aggressive treatment.
机译:主要皮肤B细胞淋巴瘤(PCBCL)比普遍认为更频繁地发生。最重要的亚型是:边缘区B细胞淋巴瘤/免疫细胞瘤,卵泡中心细胞淋巴瘤和腿部大的B细胞淋巴瘤。只有在临床发现的知识的背景下,可以呈现正确的诊断。分类和生物学方面的进展与现代技术的应用有关,包括免疫组织学和激光束微粒,然后进行分子分析。 PCBCL的未来定义将基于其分子异常及其病因和病因和发病机制。意识到PCBCL的特殊临床行为应防止不必要的侵略性处理。

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