• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文会议>International Symposium on Ceramics in Medicine >A Study of Bone-Like Apatite Formation on β-TCP/PLLA Scaffold in Static and Dynamic Simulated Body Fluid
【24h】

A Study of Bone-Like Apatite Formation on β-TCP/PLLA Scaffold in Static and Dynamic Simulated Body Fluid

机译：静态和动态模拟体液中β-TCP / PLLA支架上骨状磷灰石形成的研究

获取原文
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

The ability of apatite to form on the surface of biomaterials in simulated body fluid (SBF) has been widely used to predict the bone-bonding ability of bioceramic and bioceramic/polymer composites in vivo. Porous β-tricalcium phosphate/poly(L-lactic acid) (β-TCP/PLLA) composite scaffold was synthesized by new method. The ability of inducing calcium phosphate (Ca-P) formation was compared in static simulated body fluid(sSBF) and dynamic simulated body fluid (dSBF). The Ca-P morphology and crystal structures were identified using SEM, X-ray diffraction and Fourier transform infrared (FT-IR) spectroscopy. The results showed that the typical features of bone-like apatite formation on the surface and the inner pore wall of β-TCP/PLLA. Ca-P formation on scaffold surfaces in dSBF occurred slower than in sSBF and was more difficult with increasing flow rate of dSBF. The ability of apatite to form on β-TCP/PLLA was enhanced by effect of each other that has different degradable mechanism. Porous β-TCP/PLLA composite scaffold indicates good ability of Ca-P formation in vitro.
机译：磷灰石在模拟体液（SBF）的生物材料表面上形成的能力已被广泛用于预测体内生物陶瓷和生物陶瓷/聚合物复合材料的骨粘合能力。通过新方法合成多孔β-磷酸钙/聚（L-乳酸）（β-TCP / PLLA）复合支架。在静态模拟体液（SSBF）和动态模拟体液（DSBF）中比较诱导磷酸钙（CA-P）形成的能力。使用SEM，X射线衍射和傅里叶变换红外（FT-IR）光谱鉴定CA-P形态和晶体结构。结果表明，β-TCP / PLLA的表面和内孔壁上的骨状磷灰石形成的典型特征。在DSBF中的脚手架表面上形成CA-P形成比SSBF慢，并且随着DSBF的流速而越来越困难。通过彼此具有不同可降解机制的效果增强了磷灰石在β-TCP / PLLA上形成的能力。多孔β-TCP / PLLA复合支架表明在体外CA-P形成的良好能力。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号