Hydroxyapatite/Chondroitin Sulfate Microparticles as Time-Controlled Release Carrier of Proteins

机译：羟基磷灰石/软骨素微粒作为蛋白质的时间控释载体

获取原文

页面导航

摘要
著录项
相似文献
相关主题

摘要

Time-controlled releases of proteins from hydroxyapatite/chondroitin sulfate (HAp/ChS) spherical microparticles were achieved by the addition of zinc cation into the mixture solutions of HAp/ChS and protein as a novel formulation. The initial bursts of proteins, such as cytochrome c and bovine serum albumin, were apparently suppressed by the amount of zinc cation, which could be attributed to the formation of coordinate bonds of zinc cation among proteins and/or ChS moleculars. The increase of molecular lengths of ChS chains decreased the adsorbed amount of proteins, which did not apparently affected to the release of proteins.

机译：通过将锌阳离子加入Hap / Chs和蛋白质的混合物溶液作为一种新型制剂，通过加入Hap / Chs和蛋白质的混合物溶液来实现来自羟基磷灰石/软骨素（HAP / CHS）球形微粒的蛋白质的蛋白质的蛋白质释放。通过锌阳离子的量显然抑制了蛋白质的初始爆发，例如细胞色素C和牛血清白蛋白，这可能归因于蛋白质和/或CHS分子中锌阳离子的坐标键的形成。 CHS链的分子长度的增加降低了吸附量的蛋白质量，这对蛋白质的释放并不明显影响。

著录项

来源
《International Symposium on Ceramics in Medicine》|2007年||共4页
会议地点
作者
H. Watanabe; T. Ikoma; G. Chen; J. Tanaka;
展开▼
作者单位

展开▼
会议组织
原文格式 PDF
正文语种
中图分类 TB3-53;
关键词
Hydroxyapatite; Chondroitin Sulfate; Composite; Microparticle; Protein; Zinc; Sustained Release;

机译：羟基磷灰石;硫酸软骨素;复合材料;微粒;蛋白质;锌;持续释放;

相似文献

外文文献
中文文献
专利

1. Hydroxyapatite/Chondoroitin Sulfate Microparticles as Time-Controlled Release Carrier of Proteins [J] . H. Watanabe, T. Ikoma, G. Chen, Key Engineering Materials . 2007,第Pt2期

机译：羟基磷灰石/硫酸软骨素微粒作为蛋白质的时间控制释放载体
2. Hydroxyapatite/Chondroitin Sulfate Microparticles with Different Particle Size and its Adsorption Ability of Proteins [J] . H. Watanabe, T. lkoma, G. Chen, Key Engineering Materials . 2006,第Pt1期

机译：不同粒径的羟基磷灰石/硫酸软骨素微粒及其对蛋白质的吸附能力
3. Facile preparation of hydroxyapatite-chondroitin sulfate hybrid mesoporous microrods for controlled and sustained release of antitumor drugs [J] . Yuming Guo, Xiaoman Shi, Qilong Fang, Materials Letters . 2014,第juna15期

机译：羟基磷灰石-硫酸软骨素混合中孔微棒的简便制备用于控制和缓释抗肿瘤药物
4. Hydroxyapatite/Chondroitin Sulfate Microparticles as Time-Controlled Release Carrier of Proteins [C] . H. Watanabe, T. Ikoma, G. Chen, International Symposium on Ceramics in Medicine . 2007

机译：羟基磷灰石/软骨素微粒作为蛋白质的时间控释载体
5. Isolation and separation of the active portion in fathead minnow (Pimephales promelas) injury-released alarm cue and comparison of its anti-predator behavioural activity with chondroitin sulfate [D] . Meddah, Imane. 2016

机译：虎头鱼（Pimephales promelas）伤害释放警报提示中活性部分的分离与硫酸软骨素的抗捕食者行为活性比较
6. Chondroitin Sulfate Inhibits Monocyte Chemoattractant Protein-1 Release From 3T3-L1 Adipocytes: A New Treatment Opportunity for Obesity-Related Inflammation? [O] . Thomas V Stabler, Eulàlia Montell, Josep Vergés, 2017

机译：硫酸软骨素抑制3T3-L1脂肪细胞释放单核细胞趋化蛋白1：肥胖相关炎症的新治疗机会？
7. Hydroxyapatite/Chondroitin Sulfate Microparticles with Different Particle Size and its Adsorption Ability of Proteins [O] . H. Watanabe, T. Ikoma, G. Chen, 2016

机译：羟基磷灰石/硫酸软骨素微粒不同粒径及其对蛋白质的吸附能力
8. Enzymes in Tuberculous Lesions Hydrolyzing Protein, Hyaluronic Acid and Chondroitin Sulfate: A Study of Isolated Macrophages and Developing and Healing Rabbit BCG Lesions with Substrate Film Techniques; the Shift of Enzyme pH Optima Towards Neutrality in [R] . Tsuda, T., Dannenberg, A. M., Ando, M., 1974

机译：在结核病灶水解蛋白分解酵素，透明质酸和硫酸软骨素：隔离巨噬细胞和发展和愈合兔BCG病变与基材膜技术的研究;酶最优pH值向中性转变

Hydroxyapatite/Chondroitin Sulfate Microparticles as Time-Controlled Release Carrier of Proteins

摘要

著录项

相似文献

相关主题

期刊订阅