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Current Challenges in Meeting Global Iodine Requirements

机译:满足全球碘件要求的当前挑战

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Iodine deficiency is a global problem of immense magnitude afflicting 2 billion of the world's population. The adverse effects of iodine deficiency in humans, collectively termed iodine deficiency disorders, result from decreased thyroid hormone production and action, and vary in severity from thyroid enlargement (goiter) to severe, irreversible brain damage, termed endemic cretinism.Thyroid hormone is essential throughout life, but it is critical for normal brain development in the fetus and throughout childhood. During pregnancy, maternal thyroid hormone production must increase by 25-50% to meet maternal-fetal requirements. The principal sources of iodine in the diet include milk and dairy products, seafoods and foods with added iodized salt. Vegetabfes, fruits and cereals are generally poor sources of iodine because most of our soils and water supplies are deficient in iodine. The accepted solution to the problem is Universal Salt lodization where all salt for human and animal consumption is iodized at a level of 20-40 ug/g. In principle, mandatory fortification represents the most effective public health strategy where safety and efficacy can be assured and there is a demonstrated need for the nutrient in the population. Voluntary fortification of salt and other foods has many limitations and few benefits. Iodine supplementation is a useful, but expensive, inefficient and unsustainable strategy for preventing iodine deficiency.The current worldwide push to decrease salt intake to prevent cardiovascular disease presents an entirely new challenge in addressing iodine deficiency in both developing and developed countries.
机译:碘缺乏是一个巨大的巨大问题,占据世界上20亿人口的巨大问题。碘缺乏人类缺乏的不良反应,统一称碘缺乏症,导致甲状腺激素产生和作用减少,并且从甲状腺增大(甲状腺肿)严重程度变化,使特有的颅内损伤称为严重,不可逆的脑损伤。整个血糖激素是必不可少的生活,但对于胎儿和整个童年来说,这对正常的大脑发育至关重要。在怀孕期间,母性甲状腺激素生产必须增加25-50%,以满足母体要求。饮食中碘的主要来源包括牛奶和乳制品,海鲜和加入碘盐的食物。鸽舍,水果和谷物通常是碘的贫困来源,因为我们的大多数土壤和水供应缺乏碘。接受的问题的解决方案是普遍的盐寄生,其中所有盐和动物消耗的盐在20-40 ug / g的水平。原则上,强制性设防代表最有效的公共卫生策略,安全性和有效性可以保证,并且有一个人口营养的需要。盐和其他食物的自愿设防有许多局限性和很少的好处。碘补充是一种有用,但昂贵,效率低,不可持续的策略,可防止碘缺乏。全世界目前的推动降低盐摄入量,以防止心血管疾病在解决发展中国家和发达国家的碘缺乏方面对碘缺乏症来说。

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