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Characteristics of cognitive function in patients with higher brain dysfunction after brain injury:an event-related potential study

机译:脑损伤后脑功能障碍患者认知功能的特征:事件相关的潜在研究

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The object of the present study was to compare the effects of facial affective stimuli on visual event-related potentials (ERPs) in patients with higher brain dysfunction after brain injury and healthy controls, using photographs of babies depicting sadness (a crying face) and pleasure (a smiling face). The P300 amplitude when viewing a smiling baby was smaller than that when viewing a crying baby for healthy controls. However, the P300 amplitude was the same when viewing a smiling baby as when viewing a crying baby for the brain injury patients. The P300 latency in patients when viewing a smiling baby as well as when viewing a crying baby was obviously and significantly longer than those in healthy controls. The P300 latency was significantly and positively correlated with the dysfunction scale of working abilities and social active abilities.These results indicated that these patients were likely to have cognitive dysfunction and that ERPs are a useful biological marker for the evaluation of such patients. These differences may reflect differences in information processing resulting from emotional influences caused by visual affective stimuli.
机译:本研究的目的是比较对颅脑损伤患者和健康对照后更高的脑功能障碍的视觉事件相关电位(ERP)的面部情绪刺激的效果,使用婴儿描绘悲伤的照片(哭脸)和愉悦(笑脸)。查看婴儿微笑时,P300波幅明显高于健康对照观看听到婴儿的哭声时,小。然而,观察一个微笑宝宝的脑损伤患者观看听到婴儿的哭声时,当P300的幅度是一样的。患者P300潜伏期查看婴儿微笑时以及观看哭闹的婴儿明显比健康对照显著较长时。 P300潜伏期与工作能力和社会活动的abilities.These结果的功能障碍量表显著正相关表明,这些患者可能有认知功能障碍和ERP的是这类患者的评估有用的生物标志物。这些差异可能反映了从引起视觉情绪刺激情绪的影响导致的信息处理的差异。

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