• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文会议>International Evoked Potentials Symposium >Effects of sleep on cortical responses to noxious stimuli
【24h】

Effects of sleep on cortical responses to noxious stimuli

机译：睡眠对毒药刺激的皮质反应的影响

获取原文
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

We used magnetoencephalography (MEG) to study effects of sleep on cortical responses to noxious stimuli and to clarity the mechanisms underlying pain perception. For a noxious stimulus, painful intraepidermal electrical stimulation (ES), which selectively activates A-delta fibers, was applied to the dorsura of the left hand. While awake, subjects were asked to count the number of stimuli silently (Attention) or ignore the stimuli (Control). During sleep, magnetic fields recorded in stage 1 sleep and stage 2 sleep were analyzed. One main component at a latency around 140-160 ms was identified in the awake condition. Multiple source analysis indicated that this main component was generated by activities in the contralateral primary somatosensory cortex (SI), bilateral secondary somatosensory cortex (SII) and insular cortex. The medial temporal area (MT) and cingulate cortex were activated later than the main component. Cortical responses in the contralateral SI, ipsilateral SII and MT, bilateral insula, and cingulate cortex were significantly enhanced hi Attention as compared with Control. The main component 1M, as well as later magnetic fields, was markedly attenuated during sleep, suggesting that all these cortical areas are involved in pain cognition.
机译：我们使用了磁性脑膜图（MEG）来研究睡眠对皮质响应对有害刺激的影响，并清楚地抑制疼痛感知的机制。对于一种有害的刺激，选择性地激活α-δ纤维的痛苦的脑外化电刺激（ES）施用于左手的背部。虽然醒着，被要求对象默默地计算刺激的数量（注意）或忽略刺激（控制）。在睡眠期间，分析了在第1阶段睡眠中记录的磁场和阶段2睡眠。在醒着条件下鉴定了一个延迟延迟的一个主要成分。多种源分析表明，该主要组分由对侧原发性躯体感应型皮质（Si），双侧次要躯体感染术皮质（SII）和睑板上的活动产生。内侧颞区（MT）和CINGULATE CORTEX比主要成分激活。与对照相比，对侧Si，IpsilaTalal Sii和Mt，双侧肠溶和Mt，双侧Inslua和Cingulate皮质中的皮质反应显着提高了主体。在睡眠期间，主要成分1M以及后来的磁场显着减弱，表明所有这些皮质区域都参与了疼痛认知。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号