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首页> 外文会议>International Congress on Electrocardiology >PROGNOSTIC IMPACT OF AMIODARONE COMPARED TO D,L-SOTALOL IN PATIENTS WITH IMPLANTABLECARDIOVERTER DEFIBRILLATOR
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PROGNOSTIC IMPACT OF AMIODARONE COMPARED TO D,L-SOTALOL IN PATIENTS WITH IMPLANTABLECARDIOVERTER DEFIBRILLATOR

机译：胺碘酮对植入术治疗患者D，L-醇醇相比的预后影响

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Background: The prognostic impact of amiodarone compared to d,l-sotalol is poorly described in patients with implantable cardioverter defibrillator (ICD). Methods: One hundred five consecutive patients with ICD (61+-13 yo) in our institution were retrospectively reviewed. All patients were evaluated for all cause death and cardiac events (cardiac death, heart failure deterioration, lethal ventricular arrhythmia). Results: Amiodarone, d,l-sotalol were used to 59, 14 patients respectively. 8 patients had both amiodarone and d,l-sotalol. During mean follow up period of 31+-21 months, patients with d,l-sotalol and LVEF =40% shows no cardiac events, however frequent cardiac events were observed in patients with d,l-sotalol and LVEF <40%. A multivariate analysis of clinical variables demonstrated that the only independent clinical predictor of freedom from cardiac events for patietns with ICD and LVEF <40% was the use of amiodarone (p<0.05). Conclusion: Concomitant use of d,l-sotalol to ICD therapy benefits patients with preserved cardiac function but tend to have frequent cardiac events in patients with impaired cardiac function. On the other hand, concomitant use of amiodarone to ICD therapy prevents cardiac events in patients with impaired cardiac function.
机译：背景：氨基酮与D相比的预后影响与D，L-甲酚相比，可植入​​的心脏病患者（ICD）患者患者患者差。方法：回顾性审查了我所机构中的一百五名ICD（61 + -13 yo）的患者。所有患者均针对所有患者进行评估，所有原因死亡和心脏事件（心脏死亡，心力衰竭劣化，致命性心间心律失常）。结果：胺碘酮，D，L-醇溶醇分别用于59名，14名患者。 8名患者均具有胺碘酮和D，L-醇醇。在平均追随时间为31±21个月，D，L-甲苯醇酚和LVEF = 40％的患者显示没有心脏事件，但是在D，L-醇醇和LVEF <40％的患者中观察到频繁的心脏事件。对临床变量的多变量分析表明，使用ICD和LVEF的康复与心脏事件的自由独立临床预测因子<40％是使用胺碘酮（P <0.05）。结论：伴随着D，L-醇醇对ICD治疗的益处患者患有保存的心功能，但往往具有患者心功能受损的患者的心脏事件。另一方面，伴随着胺碘酮对ICD治疗可防止心脏功能受损患者的心脏事件。

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