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首页> 外文会议>Conference on Biomedical Thermoacoustics, Optoacoustics, and Acousto-Optics >Dual wavelength laser diode excitation source for 2D photoacoustic imaging
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Dual wavelength laser diode excitation source for 2D photoacoustic imaging

机译：用于2D光声成像的双波长激光二极管激励源

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Photoacoustic methods can be used to make spatially resolved spectroscopic measurements of blood oxygenation when using a multiwavelength excitation source, such as an OPO system. Since these excitation sources are usually expensive and bulky, an alternative is to use laser diodes. A fibre coupled laser diode excitation system has been developed, providing two wavelengths, 850 and 905nm, each composed of 6 high peak power pulsed laser diodes. The system provided variable pulse durations (65-500ns) and repetition rates of up to 5KHz. The pulse energies delivered by the excitation system at 905nm and 850nm were measured to be 120μJ and 80μJ respectively for a 200ns pulse duration. To demonstrate the utility of the system, the excitation source was combined with an ultrasound detector to form a probe for in vivo single point measurements of superficial blood vessels. Changes in blood oxygenation and volume in the finger tip were monitored while making venous and arterial occlusions. To demonstrate the imaging capability of the excitation system, 2D photoacoustic images of a physiologically realistic phantom were obtained for a range of pulse durations using a cylindrical scanning system. The phantom was composed of cylindrical absorbing elements(μ_a = 1mm~(-1)) of 2.7mm diameter, immersed in a 1% intralipid solution (μ_s = 1mm~(-1)). This study demonstrated the potential use of laser diodes as an excitation source for photoacoustic imaging of superficial vascular structures.
机译：当使用多波长激励源（例如OPO系统）时，光声方法可用于制备血氧的空间分辨光谱测量。由于这些激发源通常昂贵并且庞大，因此替代方案是使用激光二极管。已经开发了光纤耦合激光二极管激励系统，提供两个波长，850和905nm，每个波长为850和905nm，每个波长为6个高峰功率脉冲激光二极管。该系统提供了可变脉冲持续时间（65-500ns）和最多可达5kHz的重复率。由激发系统输送的脉冲能量在905nm和850nm处被测量为120μj和80μj，分别用于200ns脉冲持续时间。为了证明系统的效用，激发源与超声检测器组合，以形成浅表血管的体内单点测量的探针。在制作静脉和动脉闭塞的同时监测手指尖的血氧和体积的变化。为了证明激发系统的成像能力，使用圆柱扫描系统获得了一系列脉冲持续时间的生理学上现实幻像的2D光声图像。幻影由直径为2.7mm的圆柱形吸收元件（μ_a= 1mm〜（-1））组成，浸入1％intralipid溶液中（μ_s= 1mm〜（-1））。本研究证明了激光二极管的潜在使用作为浅表血管结构的光声成像的激发源。

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