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首页> 外文期刊>Optics Letters >Simultaneous dual-wavelength photoacoustic radar imaging using waveform engineering with mismatched frequency modulated excitation
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Simultaneous dual-wavelength photoacoustic radar imaging using waveform engineering with mismatched frequency modulated excitation

机译：使用不匹配的调频激励的波形工程同时进行双波长光声雷达成像

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摘要

The spectroscopic imaging capability of photoacoustics (PA) without the depth limitations of optical methods offers a major advantage in preclinical and clinical applications. Consecutive PA measurements with properly chosen wavelengths allow composition related information about blood or tissue. In this work, we propose and experimentally introduce modulation waveform engineering through the use of mismatched (uncorrelated or weakly correlated) linear frequency modulated signals for PA characterization and imaging. The feasibility of the method was tested on oxygen saturated hemoglobin and deoxygenated hemoglobin in vitro in a blood circulating rig. The method was also employed for in vivo imaging of a neck carcinoma tumor grown in a mouse thigh. The proposed method can increase the accuracy and speed of functional imaging by simultaneous PA probing with two wavelengths using portable laser-diode based PA imaging systems. (C) 2015 Optical Society of America
机译：不受光学方法深度限制的光声（PA）光谱成像功能在临床前和临床应用中提供了主要优势。连续PA测量结果与适当选择的波长允许围绕血液或组织成分相关的信息。在这项工作中，我们提出并通过使用不匹配的（不相关或弱相关）线性调频信号进行PA表征和成像，并通过实验介绍了调制波形工程。在血液循环装置中体外测试了氧饱和血红蛋白和脱氧血红蛋白的方法的可行性。该方法还用于在小鼠大腿中生长的颈部癌肿瘤的体内成像。所提出的方法可以通过使用基于便携式激光二极管的PA成像系统同时探测两个波长的PA来提高功能成像的准确性和速度。 （C）2015年美国眼镜学会

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