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Lack of Recovery of Baroreflex Function in Hypertensive Patients after Heart Surgery

机译:心脏手术后高血压患者中缺乏肾小球功能的复苏

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Baroreflex sensitivity (BRS) and heart rate variability (HRV) have significant influence on the patients' prognosis after cardiovascular events. The following study was performed to assess differences in the response of the autonomic regulation in hypertensive and normotensive patients undergoing cardiac surgery with heart-lung machine. 166 consecutive patients were enrolled in a prospective study; 102 of them were hypertensive according to the criteria of the WHO. Cardiovascular signals were recorded the day before, 24h after surgery and one week after surgery. SDNN steeply declined in Hypertensives 24h after the operation (46.5 vs. 24.5ms, p<10-7), the decline in Normotensives was less pronounced (52 vs. 30.8ms, p<0.01). The mean number of bradycardic fluctuations of BRS decreased in both groups at 24h, then there was recovery in Normotensives after one week, but not in Hypertensives. While the response to surgery is similar in normotensive and hypertensive patients, there obviously is a decreased ability to recover in Hypertensives.
机译:Baroreflex敏感性(BRS)和心率变异性(HRV)对心血管事件后患者预后具有显着影响。进行以下研究以评估高血压和正常血压患者自主调控响应差异的差异,与心肺机进行心脏手术。 166名连续患者注册了一项潜在的研究;根据世界卫生组织的标准,其中102人是高血压的。手术前24小时和手术后一周记录心血管信号。在操作后24小时急剧下降的SDNN(46.5与24.5ms,P <10-7),正常态度下降不太明显(52 vs.30.8ms,P <0.01)。在24小时内,Brs的平均颅卡序列的平均数量在两组中降低,然后在一周后在正常致正式逆转中恢复,但不在高血压率。虽然对手术的反应相似,但在正常和高血压患者中,虽然患有高血压和高血压患者的反应,但显然有一种降低在高血压率中恢复的能力。

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