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The Discriminatrix: A System for Discovering Microbial Biomarkers

机译:鉴别案:一种发现微生物生物标志物的系统

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Categorizing and classifying bacterial strains and species is of significant importance in the clinical setting [1]. The treatment of a patient infected with a microbe is crucially dependant on reliable early stage strain identification. Newly developed mass spectrometric methods have the potential to surpass the current time-consuming approaches. Additionally, the identification of biomarkers suitable for routine clinical application remains one of the most urgent challenges of applied proteomics. Sample heterogeneity and limited amounts of clinical samples still present a major hurdle for biomarker detection approaches.
机译:对细菌菌株和物种进行分类和分类在临床环境中具有重要意义[1]。用微生物感染的患者的治疗是至关重要的,这依赖于可靠的早期菌株鉴定。新开发的质谱方法具有超越当前耗时的方法。另外,适用于常规临床应用的生物标志物的鉴定仍然是应用蛋白质组学最紧迫的挑战之一。样品异质性和有限量的临床样品仍然存在生物标志物检测方法的主要障碍。

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