Medium Optimization for the Antibacterial Substances Production from Brevibacillus Brevis XDH Using Response Surface Methodology

机译：使用响应表面方法从Brevibacillus Brevis XDH产生的抗菌物质产生的中等优化

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Brevibacillus Brevis XDH is an antagonistic bacterium with high antibacterial activity against many pathogens. Fermentation medium for the production of the antibacterial substances was statistically optimized by Plackett-Burman design, steepest ascent experiments and response surface methodology. The optimized medium was composed of (g/L): glucose 15.6, soybean meal 28.4, starch 6, CaCO_3 2 and MgSO_4 4. After optimization, the production of antibacterial metabolites increased more than 70% than that of control.

机译：Brevibacillus Brevis XDH是一种拮抗细菌，具有高抗菌活性，用于许多病原体。用于生产抗菌物质的发酵培养基通过Plackett-Burman设计，最陡峭的上升实验和响应面方法进行了统计优化。优化的培养基由（G / L）：葡萄糖15.6，大豆饭28.4，淀粉6，CaCO_3 2和MgSO_4 4.优化后，抗菌代谢物的产生比对照的增加超过70％。

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《International Conference on Smart Materials and Nanotechnology in Engineering》|2012年||共6页
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作者
Zhen Song; Xunli Liu; Changxu Lu; Jian Yu; Ruicheng Ju; Yuhua Zhao; Jinyu Li; Kaiqi Liu;
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中图分类 TB383-532;
关键词
Brevibacillus brevis; Medium optimization; Response surface methodology;

机译：Brevibacillus brevis;中优化;响应面方法;

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Medium Optimization for the Antibacterial Substances Production from Brevibacillus Brevis XDH Using Response Surface Methodology

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