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首页> 外文会议>International Conference on Smart Materials and Nanotechnology in Engineering >Study on the Hypolipidemic Effect and Antioxidant activity of Seabuckthorn Marc Flavonoids
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Study on the Hypolipidemic Effect and Antioxidant activity of Seabuckthorn Marc Flavonoids

机译：Seabuckthorn MARC黄酮类化合物的低血脂效应和抗氧化活性研究

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摘要

The hypolipidemic effect and anti-oxidative activity of seabuckthorn marc flavonoids (SMF) on hyperlipidemic rats was investigated. The rats were divided into 5 groups, including normal control group, hyperlipidemic model control group and 3 different doses of SMF groups i.e. 3.0 mg/kg·bw, 30.0 mg/kg·bw, 90mg/kg·bw, respectively. The SMF was given orally for 35 days. After the treatment, the body, fat and liver weights of rats were weighed. The content of serum total triglycerides (TG), total cholesterol (TC), high density lipoprotein cholesterol (HDL-C), low density lipoprotein cholesterol (LDL-C) and the activity of lipid metabolism and anti-oxidative enzyme were determined. The levels of serum lipids in hyperlipidemic rats fed with SMF were significantly lower than model control group. The activities of hepatic lipase (HL), lipoprotein lipase (LPL), lipidase (LPS), superoxide dismutase (SOD), glutathione (GSH) in liver were increased, while the contents of malondialdehyde (MDA) were decreased in SMF groups. The results indicate that SMF has significantly hypolipidemic effects and antioxidant activity.
机译：研究了对高脂质化大鼠海库斯马库尔黄酮类药物（SMF）的抗脂血糖效应和抗氧化活性。将大鼠分成5组，包括正常对照组，高脂血症模型对照组和3个不同剂量的SMF组即3.0毫克/千克体重·的，30.0毫克/千克体重·，90毫克/公斤·体重，分别。 SMF口服35天。治疗后，称量大鼠的身体，脂肪和肝脏重量。确定血清总甘油三酯（TG），总胆固醇（TC），高密度脂蛋白胆固醇（HDL-C），低密度脂蛋白胆固醇（LDL-C）和脂质代谢活性和抗氧化酶的含量。用SMF喂养的高脂质血症大鼠血清脂质的水平显着低于模型对照组。肝脂肪酶（H1），脂蛋白脂肪酶（LPL），脂质酶（LPS），超氧化物歧化酶（SOD），肝脏（GSH），谷胱甘肽（GSH）的活性增加，而丙二醛（MDA）的含量在SMF基团下降。结果表明，SMF具有显着的低血脂效应和抗氧化活性。

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