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Antibiotic Resistance Patterns of Escherichia coli in Pediatric Urinary Tract Infections for the years 2001 -2008

机译:2001年儿科尿路感染大肠杆菌抗生素抗性模式2001 -2008

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Although the changing patterns of antimicrobial resistance in urinary tract infection (UTI) are different in geographic regions, resistance of the urine isolates to commonly used antibiotics has increased significantly in many countries. We conducted a retrospective analysis to assess the change of antibiotic resistance of Escherichia coli (E. coli) in pediatric patients aged 0-15 years. Because the resistance rate of E. coli to ampicillin, co-trimoxazole, gentamicin, and first-generation cephalosporins were high, amoxicillin-clavulanic acid, second-generation cephalosporins, and amikacin could be reasonable alternative in the empirical treatment of the first UTI in children. Interestingly, there was a trend toward decreasing resistance of gentamicin, cephalothin, and cefotaxime in our region. However it is unknown that decreased antimicrobial resistance was also occurred in other regions in our country, so further epidemiologic data in several regions will be necessary to confirm our data.
机译:虽然尿路感染(UTI)在地理区域中的抗微生物抗性的变化模式不同,但许多国家的尿液分离株对常用抗生素的抗性显着增加。我们进行了回顾性分析,以评估0-15岁的儿科患者中大肠杆菌(大肠杆菌)的抗生素抗性变化。因为大肠杆菌对氨苄青霉素,共析唑,庆大霉素和第一代头孢菌素的抵抗率高,阿莫西林 - 克拉维酸,第二代头孢菌素和Amikacin可以是第一个UTI的经验处理的合理替代方案孩子们。有趣的是,在我们地区的庆大霉素,头孢噻吩和头孢噻肟的抗性有一种趋势。然而,尚不清楚的是,在我国的其他地区也发生了降低的抗微生物抗性,因此需要在若干地区进一步的流行病学数据来确认我们的数据。

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