• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文会议>American Society for Mass Spectrometry Conference on Mass Spectrometry and Allied Topics >Comprehensive Plasma Analysis for Finding Pathogenic Factors in Preeclampsia
【24h】

Comprehensive Plasma Analysis for Finding Pathogenic Factors in Preeclampsia

机译：综合等离子体分析，用于寻找预贷款血清血清致病因子

获取原文
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

About 8percent of pregnant women develop preeclampsia that has resulted in substantial increase in fetal morbidity and mortality. Finding the pathogenic factors of preeclampsia is important for understanding the pathogenesis mechanisms and for early diagnosis of preeclampsia. In the present study, a comprehensive plasma analysis has been carried out aiming to identify pathogenic factors in preeclampsia. We have used a novel depletion method based on peptide library affinity chromatography to reduce the concentration difference of plasma proteins that allows us to identify a large number of proteins in low abundance. Differentially expressed proteins were also identified and compared from plasma samples of normal pregnant women and preeclampsia patients.
机译：关于孕妇的8个孕妇开发出胎儿发病率和死亡率大幅增加的先兆子痫。寻找先兆子痫的致病因子对于了解发病机制和早期诊断前胰蛋白酶的致病因素是重要的。在本研究中，已经进行了综合等离子体分析，旨在鉴定预坦克西亚的病原因子。我们使用了基于肽库亲和色谱法的新型耗尽方法，以降低允许我们在低丰度中识别大量蛋白质的血浆蛋白质的浓度差异。还鉴定了差异表达的蛋白质，并与常规孕妇和预先普利坦斯患者的血浆样品进行了鉴定和比较。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号