EFFECT OF LIGAND BINDING ON CONFORMATIONAL DYNAMICS OF DAHP SYNTHASE USING MICROFLUIDICS ENABLED HYDROGEN/DEUTERIUM EXCHANGE

机译：用微流体氢/氘交换用微流体氢气与氘代交换的DAHP合酶构象动态的影响

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Our novel microfluidic device enables direct measurements of site specific dynamics in weakly structured regions of a protein. We were able to demonstrate the structural consequences of ligand binding.

机译：我们的新型微流体装置能够在蛋白质的弱结构区域中直接测量位点特异性动态。我们能够证明配体结合的结构后果。

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《American Society for Mass Spectrometry Conference on Mass Spectrometry and Allied Topics》|2013年||共1页
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Tamanna Rob; Naresh Balachandran; Paul Berti; Derek J. Wilson;
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中图分类 TB994.5-53;
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1. Mapping ligand binding using microfluidics-enabled millisecond timescale hydrogen-deuterium exchange [J] . Diana Resetca, Derek J. Wilson International journal of mass spectrometry . 2017,第期

机译：使用Microfluicics的毫秒时间粒子氢氘交换进行映射配体结合
2. Ligand binding and conformational dynamics in a flavin-based electron-bifurcating enzyme complex revealed by Hydrogen-Deuterium Exchange Mass Spectrometry [J] . Demmer Julius K., Rupprecht Fiona A., Eisinger Martin L., FEBS letters. . 2016,第24期

机译：氢-氘交换质谱显示基于黄素的电子分叉酶复合物中的配体结合和构象动力学
3. Ligand binding and conformational dynamics in a flavin‐based electron‐bifurcating enzyme complex revealed by Hydrogen–Deuterium Exchange Mass Spectrometry [J] . FEBS Letters . 2016,第24期

机译：氢-氘交换质谱显示基于黄素的电子分叉酶复合物中的配体结合和构象动力学
4. EFFECT OF LIGAND BINDING ON CONFORMATIONAL DYNAMICS OF DAHP SYNTHASE USING MICROFLUIDICS ENABLED HYDROGEN/DEUTERIUM EXCHANGE [C] . Tamanna Rob, Naresh Balachandran, Paul Berti, American Society for Mass Spectrometry Conference on Mass Spectrometry and Allied Topics . 2013

机译：用微流体氢/氘交换用微流体氢气与氘代交换的DAHP合酶构象动态的影响
5. Probing protein small ligand binding dynamics by hydrogen/deuterium exchange and electrospray ionization mass spectrometry. [D] . Xiao, Hui. 2005

机译：通过氢/氘交换和电喷雾电离质谱探测蛋白质小配体结合动力学。
6. Conformational changes of the glucocorticoid receptor ligand binding domain induced by ligand and cofactor binding and the location of cofactor binding sites determined by hydrogen/deuterium exchange mass spectrometry [O] . Lee Frego, Walter Davidson 2006

机译：配体和辅因子结合引起的糖皮质激素受体配体结合域的构象变化以及氢/氘交换质谱法测定的辅因子结合位点的位置
7. Conformational changes of the glucocorticoid receptor ligand binding domain induced by ligand and cofactor binding, and the location of cofactor binding sites determined by hydrogen/deuterium exchange mass spectrometry [O] . Frego, Lee, Davidson, Walter 2006

机译：配体和辅因子结合引起的糖皮质激素受体配体结合域的构象变化，以及氢/氘交换质谱法测定的辅因子结合位点的位置

EFFECT OF LIGAND BINDING ON CONFORMATIONAL DYNAMICS OF DAHP SYNTHASE USING MICROFLUIDICS ENABLED HYDROGEN/DEUTERIUM EXCHANGE

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