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首页> 外文会议>International conference on biomagnetism advances in biomagnetism >Early ERF Responses to Final Words in a Sentence Context during Reading in Individuals with Autism Spectrum Disorders: An MEG Study
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Early ERF Responses to Final Words in a Sentence Context during Reading in Individuals with Autism Spectrum Disorders: An MEG Study

机译：早期ERF在读取句子上下语境中的最终词语在读取自闭症谱系障碍的个人期间：MEG研究

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This study used magnetoencephalography (MEG) to study the neural basis of abnormalities in sentence context effects in individuals with an autism spectrum disorder (ASD) and typically developing (TD) individuals. Early ERF responses (~150ms) to three different types of final words Idominant homonyms (DH), subordinate homonyms (SH), unambiguous words (UW)| were analyzed. In both participant groups, strong responses were observed at word response latency over left-occipito and mid-parietal regions. There were no significant differences between the participant groups in any of the final words at 150ms. The neural responses, however, were significantly modulated by the final word category within groups. In TD, the response to UW was significantly different than both DH and SH predominantly over the left hemisphere. There were no differences between DH and SH conditions in TD individuals. On the other hand, in ASD, there was a significant difference between each paired final word condition, where significant responses were observed mainly over the right hemisphere. These results are consistent with the argument that early semantic access takes place as early as 150ms after the onset of a word. Moreover, these findings suggest atypical semantic representations for more and less frequent meanings of the homonyms in individuals with ASD.
机译：本研究使用了磁性脑图（MEG）来研究句子情报（ASD）和通常发展（TD）个体的个体中句子背景效应的神经基础。早期的ERF响应（〜150ms）到三种不同类型的最终单词idominant同音异音（DH），下属同音异义（SH），明确的单词（UW）|分析了。在两个参与者群体中，在左枕和中间地区的词响应延迟下观察到强烈反应。参与者组在150ms的任何最后单词中没有显着差异。然而，神经响应被组内的最终单词类别显着调节。在TD中，对UW的响应显着不同于DH和SH，主要在左半球上方。 TD个人的DH和SH条件之间没有差异。另一方面，在ASD中，每个成对的最终词条条件之间存在显着差异，其中主要在右半球上观察到了显着的反应。这些结果与早期语义访问在一个单词发作后早期发生的参数一致。此外，这些研究结果表明了非典型的语义表示，以便在亚本色的个人中的谐音越来越少。

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