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Intravascular large cell lymphoma(IVLBCL) An autopsy study-

机译:血管内大细胞淋巴瘤(IVLBCL)尸检研究 -

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Histological and immunohistochemical studies of an autopsy case with IVLBCL, Asian variant, was presented. Large atypical tumor cells with a large prominent nucleolus were proliferated almost exclusively in the wall and /or lumen mostly of capillaries and smaller blood vessels of almost all organs and tissues.However, most lymph nodes escaped tumor involvement except a part of a lymph node Skin involvement could not be confirmed. Immunohistochemically, tumor cells were reactive for CD20 and CD79α but unreactive for CD3 and CD5. Cardiomegaly, hepatosplenomegaly, erythrophagia, pancytopenia, multiorgan failure indicated Asian variant of IVLBCL. Multiorgan failure due to intra- and extra-vascular marked proliferation of tumor cells and shock were thought to be the cause of death.
机译:提出了IVLBCL,亚洲变体的尸检壳的组织学和免疫组化研究。具有大的突出核仁的大型非典型肿瘤细胞几乎完全在壁上和/或腔大部分的毛细管和几乎所有器官和组织的较小血管。然而,除了淋巴结皮肤的一部分之外,大多数淋巴结逸出肿瘤受累参与无法确认。免疫组织化学,肿瘤细胞对于CD20和CD79α是反应性,但对CD3和CD5的不应相关性。心肌细菌,肝瓣,肝癌,韧皮病,术失败表明IVLBCL的亚洲变体。由于肿瘤细胞的肿瘤细胞和血管内显着的增殖而导致的多核失败被认为是死亡的原因。

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