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Impact of H. pylori Eradication on Gastric Atrophy: Current Status of the Japanese Intervention Trial (JITHP Study)

机译：H.幽门螺杆菌根除对胃萎缩的影响：日本干预审判的现状（JITPP研究）

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The Japanese Intervention Trial of H. Pylori (JITHP) was originally designed to elucidate the causal link between H. Pylori, gastric pre-malignant conditions and gastric cancer. However, due to the final number of recruitments the endpoints were reduced to determine the causality between eradication and regression/progression of atrophy. H. pylori positive patients were randomized to receive a seven days course of Lansoprazpl, Claritromycin and Amoxicilin. Atrophy was evaluated endoscopically according to Kimura-Takemoto's classification. Since September 1995, 8322 subjects were screened serologically. Among 4650 positive subjects, 1222 were endoscopically screened.

机译：日本幽门螺杆菌（JITHP）的日本干预试验最初旨在阐明H. Pylori，胃癌患者和胃癌之间的因果关系。但是，由于最终招聘数量，终点被降低，以确定根除和消退/萎缩进展之间的因果关系。 H. Pylori阳性患者随机患者接受七天的LansoPrazpl，Clytromycin和Amoxicilin。根据Kimura-Takemoto的分类，内窥镜评估萎缩。自1995年9月以来，筛选8322名受试者筛查。在4650个阳性受试者中，1222例在内窥镜上筛选。

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《International Gastric Cancer Congress》|2005年||共6页
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D Saito; N. Boku; T. Fujioka; Y. Fukuda; Y. Matsushim;
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中图分类胃肿瘤;
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1. Eradication Therapy for Helicobacter pylori Improves Nutrition Status Depended on Severity of Gastric Mucosal Atrophy and Plasma Ghrelin Level in Japanese Hemodialysis Patients [J] . Sugimoto Mitsushige, Otsuka Taketo, Murata Masaki, The American Journal of Gastroenterology . 2018,第Suppla2期

机译：幽门螺杆菌的根除治疗改善了日本血液透析患者胃粘膜萎缩和血浆Ghrelin水平的严重程度依赖营养状态
2. Current status of Japanese H. pylori eradication therapy based on a nationwide clinical database analysis [J] . Murakami K., Deguchi H., Uda A., Helicobacter . 2017,第S1期

机译：基于全国范围的临床数据库分析的日本H.幽门螺杆菌根除治疗现状
3. Clinical trial: irsogladine maleate, a mucosal protective drug, accelerates gastric ulcer healing after treatment for eradication of Helicobacter pylori infection--the results of a multicentre, double-blind, randomized clinical trial (IMPACT study). [J] . Hiraishi H, Haruma K, Miwa H, Alimentary pharmacology & therapeutics. . 2010,第8期

机译：临床试验：粘膜保护药马来酸伊索格列定在根除幽门螺杆菌感染的治疗后加速胃溃疡的愈合-多中心，双盲，随机临床试验的结果（IMPACT研究）。
4. Impact of H. pylori Eradication on Gastric Atrophy: Current Status of the Japanese Intervention Trial (JITHP Study) [C] . D Saito, N. Boku, T. Fujioka, International Gastric Cancer Congress . 2005

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5. Helicobacter pylori (HP) infection alone, but not HP-induced atrophic gastritis, increases the risk of gastric lymphoma: a case-control study in Japan [D] . Ishikura Naoyo, 石倉直世 2019

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6. Helicobacter pylori and gastric cancer: current status of the Austrain-Czech-German gastric cancer prevention trial (PRISMA-Study) [O] . S. Miehlke, C. Kirsch, B. Dragosics, 2001

机译：幽门螺杆菌和胃癌：奥地利-捷克-德国胃癌预防试验的现状（PRISMA-研究）
7. Associations of Interleukin-1β with H. pylori-Induced Gastric Atrophy and Syndrome of Dampness-Heat in the Spleen and Stomach in Subjects with H. pylori-Related Gastric Diseases [O] . Yunzhan Zhang, Xu Chen, Lin Gong, 2020

机译：白细胞介素-1β与H.幽门螺杆菌诱导的胃萎缩和湿热症综合征在脾脏和胃中的H.幽门螺杆菌相关胃病中的胃窦

Impact of H. pylori Eradication on Gastric Atrophy: Current Status of the Japanese Intervention Trial (JITHP Study)

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