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>Prognostic Factors in a Series of 1074 Patients with Gastric Carcinoma Undergoing Surgical Resection at a Single Western Institution
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Prognostic Factors in a Series of 1074 Patients with Gastric Carcinoma Undergoing Surgical Resection at a Single Western Institution
The aim of our study was to identify clinicopathological predictors of survival among patients undergoing potentially curative resections for gastric carcinoma. From January 1987-March 2004, 1074 patients have been submitted to curative gastric resection for gastric cancer. The surgical procedure consisted of 289 (27%) total and 785 (63%) subtotal gastrectomies. The extent of lymph node dissection was limited Dl (n=376, 35%) or extended D2 (N=578, 54%) and D3 (n=12, 1%); no lymphadenectomy was performed in 108 (10%) cases. The distribution of N stage was: N0=278 (26%), Nl=344 (32%); N2=215 (20%); N3=129 (12%). Univariate analyses were performed for gender, age, pT stage, pN stage, tumor site, tumor size, and extent of lymphadenectomy. Significant factors were then entered into a Cox regression analysis. CONCLUSIONS: T stage, N stage, and extent of lymphadenectomy were all independent predictors of survival in patients submitted to curative gastric resections.
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