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首页> 外文会议>International Gastric Cancer Congress >Usefulness of a novel electrosurgical knife, IT knife-2, for endoscopic submucosal dissection of early gastric cancer
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Usefulness of a novel electrosurgical knife, IT knife-2, for endoscopic submucosal dissection of early gastric cancer

机译：一种新型电外科刀，IT刀2，用于早期胃癌的内窥镜粘膜粘膜膜的有用性

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Background and study aims: Although endoscopic submucosal dissection (ESD) of early gastric cancer using the insulation-tipped diathermic (IT) knife enables removal of large and ulcerative lesions en bloc, expert endoscopic skill is required. We developed an improved IT knife (IT-2) and compared its efficacy and safety with the original IT knife (IT-OM).Patients and methods: We performed ESD of 602 gastric cancers. Of these, 314 previously untreated single lesions of initial onset were analyzed. Operating time, rate of en bloc resection and incidence of complications in the IT-2 group (161 patients) and IT-OM group (153 patients) were compared. Lesions were further analyzed as to whether they met the Japanese Gastric Cancer Association indications for ESD or extended indications.Results: Mean resection time was significantly shorter in the IT-2 than in the IT-OM group (48 vs. 63 min). Surgeries longer than 2 h were fewer in the IT-2 than in the IT-OM group (3% vs 12%). En bloc and margin-free resection rates in the IT-OM and IT-2 groups were 95% and 99%, respectively. Perforations occurred in 3.9% of IT-OM cases and 5% of IT-2 cases (N.S.). Rate of postoperative hemorrhage was 7.8% and 8.7% for IT-OM and IT-2 groups, respectively (N.S.). In both groups, complications were treated endoscopically, and emergency surgery was unnecessary.Conclusions: Resectability and complication rates were similar between the two groups. However, operating time was shorter with IT-2, irrespective of the criteria for performance of ESD. This study suggests benefits of the IT-2 over the IT-OM.
机译：背景和研究旨在：虽然使用绝缘挖透热疗法（IT）刀的早期胃癌的内窥镜粘膜粘膜（ESD）能够去除大型和溃疡性病变，所需的专家内窥镜技能。我们开发了一种改进的IT刀（IT-2）并将其与原始IT刀（IT-OM）的疗效和安全性进行了比较.Patiants和方法：我们进行了602例胃癌的ESD。其中，分析了314例之前未经处理的单一病变的初始发作。比较IT-2组（161例）和IT-OM组（153名患者）中的经营时间，en Bloc切除和并发症发病率。进一步分析病变，以达到ESD或扩展适应症的日本胃癌关联适应症。结果：意味着在IT-2中比IT-OM组（48对63分钟）显着短。在IT-2中长于2小时的手术比IT-OM组更少（3％vs 12％）。 IT-OM和IT-2组中的无缘和边缘切除率分别为95％和99％。穿孔发生在3.9％的IT-OM案件中，5％的IT-2案例（N.S.）。术后出血率分别为IT-OM和IT-2组的7.8％和8.7％（N.S.）。在这两组中，在内窥镜上治疗并发症，不必要的急诊手术。结论：两组之间的可分离性和并发症率相似。然而，运行时间与IT-2较短，无论ESD性能的标准如何。本研究表明IT-2在IT-OM上的益处。

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