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Global coordination for swine influenza virus surveillance and research: What are we missing from the big picture ?

机译:猪流感病毒监测与研究的全球协调:我们从大局中失踪了什么?

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Surveillance for influenza A viruses (IAV) circulating in pigs and other non-human mammals has been chronically underfunded and virtually nonexistent in many areas of the world. This deficit continues in spite of our knowledge that influenza is a disease shared between man and pig from at least as far back as the 1918 Spanish Flu Pandemic. In March-April 2009, a novel pandemic H1N1 emerged in the human population in North America and demonstrated in a very public forum the paucity of data on influenza viruses in swine. This scrutiny continues. The gene constellation of the emerging virus was demonstrated to be a combination of genes from swine influenza A viruses (SIV) of North American and Eurasian lineages that had never before been identified inswine or other species. The emergent H1N1 quickly spread in the human population and the outbreak reached pandemic level 6 as declared by the World Health Organization on June 11,2009. Although the 8 gene segments of the novel virus are similar to available sequences of corresponding genes from SIV from North America and Eurasia, no closely related ancestral IAV with this gene combination had been identified in North America or elsewhere in the world. Other than sporadic transmission to humans, swine influenza A viruses of the H1N1
机译:流感的监测猪和其他非人类哺乳动物循环的病毒(IAV)已经长期抵消,在世界许多地区几乎不存在。尽管我们知道,这种赤字仍在继续流感是人和猪之间共享的疾病,至少与1918年西班牙流感大流行一样。 2009年3月 - 4月,北美人类人口中出现了一部小型大流行H1N1,并在一个非常公共论坛上展示了猪流感病毒数据的缺乏。这个审查继续。表明新兴病毒的基因星座是北美和欧亚血管分析中从未识别出inswine或其他物种的猪流感病毒(siv)的基因组合。新兴H1N1在6,2009年6月11日宣布世界卫生组织宣布的人口迅速蔓延,爆发达到大流行水平6。尽管新型病毒的8个基因段类似于来自北美和欧亚欧亚的SIV的相应基因的可用序列,但没有密切相关的祖先IAV,在北美或世界其他地方已经确定了这种基因组合。除了零星传播到人类,猪流感的H1N1病毒

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